A phase two randomised controlled double blind trial of high dose intravenous methylprednisolone and oral prednisolone versus intravenous normal saline and oral prednisolone in individuals with leprosy type 1 reactions and/or nerve function impairment. [PDF]
BACKGROUND: Leprosy Type 1 reactions are a major cause of nerve damage and the preventable disability that results. Type 1 reactions are treated with oral corticosteroids and there are few data to support the optimal dose and duration of treatment.
Dhakal, Sushmita +38 more
core +1 more source
Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]
Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Raewer, Helen-Caroline +7 more
core +1 more source
Iatrogenic meningitis can be caused by a number of mechanisms. The recent case reports of fungal meningitis after application of epidural methylprednisolone caused warning in the medical community.
Eduardo Genaro Mutarelli, Tarso Adoni
doaj +1 more source
Traumatic spinal cord injury (TSCI) leads to pathological changes such as inflammation, edema, and neuronal apoptosis. Methylprednisolone (MP) is a glucocorticoid that has a variety of beneficial effects, including decreasing inflammation and ischemic ...
Hong-jun Zou +4 more
doaj +1 more source
Intravenous methylprednisolone pulse therapy for children with epileptic encephalopathy [PDF]
The aim of this retrospective study of children affected by epileptic encephalopathy was to evaluate seizure frequency, electroencephalographic pattern and neuropsychological status, before and after intravenous methylprednisolone therapy.
G. Randazzo +14 more
core +4 more sources
Objective: To compare the efficacy of intra-articular injection of methyl prednisolone with ketorolac for improvement in range of motion in various shoulder joint disorders. Study Design: Quasi-experimental study.
Sumeera Matee +5 more
doaj +1 more source
Giant cell arteritis. Part III. New trends in its treatment (role of genetically engineered drugs)
Giant cell arteritis (GCA) is a well-known vasculitis sensitive to glucocorticoid (GC) immuno-suppression. However, during long-term treatment there may be many adverse reactions that remain a serious problem so far.
Azamat Makhmudovich Satybaldyev
doaj +1 more source
Long-term follow-up of intratympanic methylprednisolone versus gentamicin in patients with unilateral Menière’s disease [PDF]
Objectives: To determine whether long term (>48 months) symptomatic vertigo control is sustained in patients with Menie`re’s disease from a previous comparative trial of intratympanic methylprednisolone versus gentamicin, and if the two treatments remain
Bronstein, A.M. +23 more
core +1 more source
INTRODUCTION: Spondyloarthropathies are a group of chronic inflammatory diseases with specific clinical symptoms in rheumatic diseases. These patients suffer from pain in the joints.
Movaffagh, Nooshin +9 more
core +1 more source
The CRASH trial protocol (Corticosteroid randomisation after significant head injury) [ISRCTN74459797]. [PDF]
BACKGROUND: Worldwide, millions of people are treated each year for significant head injury. A substantial proportion die, and many more are disabled.
The CRASH trial collaborators +2 more
core +2 more sources

