A phase two randomised controlled double blind trial of high dose intravenous methylprednisolone and oral prednisolone versus intravenous normal saline and oral prednisolone in individuals with leprosy type 1 reactions and/or nerve function impairment. [PDF]
BACKGROUND: Leprosy Type 1 reactions are a major cause of nerve damage and the preventable disability that results. Type 1 reactions are treated with oral corticosteroids and there are few data to support the optimal dose and duration of treatment.
Dhakal, Sushmita +38 more
core +1 more source
Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]
Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Raewer, Helen-Caroline +7 more
core +1 more source
INTRODUCTION: Spondyloarthropathies are a group of chronic inflammatory diseases with specific clinical symptoms in rheumatic diseases. These patients suffer from pain in the joints.
Movaffagh, Nooshin +9 more
core +1 more source
Long-term follow-up of intratympanic methylprednisolone versus gentamicin in patients with unilateral Menière’s disease [PDF]
Objectives: To determine whether long term (>48 months) symptomatic vertigo control is sustained in patients with Menie`re’s disease from a previous comparative trial of intratympanic methylprednisolone versus gentamicin, and if the two treatments remain
Bronstein, A.M. +23 more
core +1 more source
Objective: To compare the efficacy of intra-articular injection of methyl prednisolone with ketorolac for improvement in range of motion in various shoulder joint disorders. Study Design: Quasi-experimental study.
Sumeera Matee +5 more
doaj +1 more source
Giant cell arteritis. Part III. New trends in its treatment (role of genetically engineered drugs)
Giant cell arteritis (GCA) is a well-known vasculitis sensitive to glucocorticoid (GC) immuno-suppression. However, during long-term treatment there may be many adverse reactions that remain a serious problem so far.
Azamat Makhmudovich Satybaldyev
doaj +1 more source
The CRASH trial protocol (Corticosteroid randomisation after significant head injury) [ISRCTN74459797]. [PDF]
BACKGROUND: Worldwide, millions of people are treated each year for significant head injury. A substantial proportion die, and many more are disabled.
The CRASH trial collaborators +2 more
core +1 more source
Refractive status and histological changes after posterior scleral reinforcement in guinea pig [PDF]
AIM: To investigate the refractive and the histological changes in guinea pig eyes after posterior scleral reinforcement with scleral allografts. METHODS: Four-week-old guinea pigs were implanted with scleral allografts, and the changes of refraction ...
Yu-Yan Huang +6 more
doaj +1 more source
Primary progressive multiple sclerosis (PPMS) is defined clinically with a progressive course from onset. There is no approved treatment for the PPMS. Methylprednisolone IV (MP) hastens the recovery from MS relapses.
Edmar A.S. de Araújo +1 more
doaj +1 more source
Pruritic annular and vesicular eruption on trunk and extremities
We report a case of linear IgA bullous dermatosis, a rare autoimmune blistering disorder that usually presents with the abrupt onset of tense bullae. We also emphasize the importance of direct immunofluorescence for the definitive diagnosis.
Dimitra Koumaki +11 more
doaj +1 more source

