Refractive status and histological changes after posterior scleral reinforcement in guinea pig [PDF]
AIM: To investigate the refractive and the histological changes in guinea pig eyes after posterior scleral reinforcement with scleral allografts. METHODS: Four-week-old guinea pigs were implanted with scleral allografts, and the changes of refraction ...
Yu-Yan Huang +6 more
doaj +1 more source
Intratympanic methylprednisolone versus gentamicin in patients with unilateral Ménière's disease: a randomised, double-blind, comparative effectiveness trial [PDF]
BACKGROUND: Ménière's disease is characterised by severe vertigo attacks and hearing loss. Intratympanic gentamicin, the standard treatment for refractory Ménière's disease, reduces vertigo, but damages vestibular function and can worsen hearing.
Seemungal, Barry M +36 more
core +1 more source
Primary progressive multiple sclerosis (PPMS) is defined clinically with a progressive course from onset. There is no approved treatment for the PPMS. Methylprednisolone IV (MP) hastens the recovery from MS relapses.
Edmar A.S. de Araújo +1 more
doaj +1 more source
Pruritic annular and vesicular eruption on trunk and extremities
We report a case of linear IgA bullous dermatosis, a rare autoimmune blistering disorder that usually presents with the abrupt onset of tense bullae. We also emphasize the importance of direct immunofluorescence for the definitive diagnosis.
Dimitra Koumaki +11 more
doaj +1 more source
A case of ANA-negative systemic sclerosis treated with methylprednisolone [PDF]
Background: Systemic sclerosis is a multi-systemic disease characterized by excessive fibrosis, inflammation, and vasculopathy. Common clinical features include skin thickening, telangiectasias, salt and pepper skin, beak-shaped nose, and microstomy ...
Carminda P. Rogacion +3 more
doaj +1 more source
Methylprednisolone-Responsive Leptospiral Acute Pulmonary Syndrome: A Case Report
Background: Leptospirosis is an infectious disease caused by the spirochete of the genus leptospira. It is thought to be the most common zoonosis globally and has a wide range of clinical presentations with pulmonary hemorrhage being one of its most ...
Iman D. Johan-Arief, +4 more
doaj +1 more source
Introduction Apalutamide is a new second‐generation anti‐androgen agent approved in 2019 for the treatment of metastatic, castration‐sensitive, and non‐metastatic, castration‐resistant prostate cancer.
Fumiaki Kirishima +2 more
doaj +1 more source
Background: Mycobacterium tuberculosis (M. tuberculosis) is the causative agent of tuberculosis. As an important component of host immunity, macrophages are not only the first line of defense against M.
Anlong Li +11 more
doaj +1 more source
Revisited Pharmacokinetic Profiles of Methylprednisolone in Plasma and Urine After Single and Multiple Oral Administrations: Relevance in Sports Drug Testing. [PDF]
Coll S +5 more
europepmc +3 more sources
Assessment of potential cardiotoxic side effects of mitoxantrone in patients with multiple sclerosis [PDF]
Previous studies showed that mitoxantrone can reduce disability progression in patients with multiple sclerosis (MS). There is, however, concern that it may cause irreversible cardiomyopathy with reduced left ventricular (LV) ejection fraction (EF) and ...
Zingler, V. C. +6 more
core +1 more source

