Results 31 to 40 of about 132,460 (340)

A novel human glucocorticoid receptor SNP results in increased transactivation potential. [PDF]

open access: yes, 2017
Glucocorticoids are one of the most widely used therapeutics in the treatment of a variety of inflammatory disorders. However, it is known that there are variable patient responses to glucocorticoid treatment; there are responders and non-responders, or ...
Cho, Kiho   +5 more
core   +3 more sources

BOUGIE DILATATION IN BENIGN ESOPHAGEAL STRICTURES: EVALUATION OF ADJUVANT METHYLPREDNISOLONE INJECTION

open access: yesİstanbul Tıp Fakültesi Dergisi, 2022
Objective: Mechanical dilatation and adjuvant injection of triamcinolone acetate (TA) effectively preserve the opening provided and reduce the number of bougie dilation (BD) in benign esophageal strictures. In this study, we aimed to evaluate the role of
İbrahim Hakkı Köker, Hakan Şentürk
doaj   +1 more source

Steroid induced osteonecrosis: An analysis of steroid dosing risk. [PDF]

open access: yes, 2010
Osteonecrosis is a serious condition involving bone destruction that frequently requires surgical treatment to rebuild the joint. While there is an abundance of literature documenting corticosteroid related osteonecrosis, there is no consensus as to the ...
Chang, Christopher   +4 more
core   +1 more source

Methylprednisolone Decreases Mitochondria-Mediated Apoptosis and Autophagy Dysfunction in Hepatocytes of Experimental Autoimmune Hepatitis Model via the Akt/mTOR Signaling

open access: yesFrontiers in Pharmacology, 2019
Autoimmune hepatitis (AIH) is characterized by massive immune cell-mediated hepatocyte destruction. Glucocorticoids, particularly methylprednisolone (MP), are the most effective treatment for AIH; however, the mechanism underlying the effects of ...
Xiaoli Fan   +7 more
doaj   +1 more source

Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature [PDF]

open access: yes, 2015
Macrophage activation syndrome (MAS) is a potentially fatal condition. It is a rare complication of several autoimmune disorders, including systemic lupus erythematosus (SLE) and systemic juvenile idiopathic arthritis (sJIA).
Didona, Dario   +4 more
core   +4 more sources

EVALUATION OF EFFICIENCY OF ENDOCRINE OPHTHALMOPATHY TREATMENT

open access: yesŽurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
Background. The achievements of modern medicine contribute to the timely diagnosis of endocrine ophthalmopathy (EOP). However, treatment continues to be a complex task, the results of which do not satisfy the physician and the patient. Purpose of the
Krinets Zh., Krasilnikova V., Dudich O.
doaj   +1 more source

Methylprednisolone versus intravenous immune globulin as an initial therapy in adult primary immune thrombocytopenia [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2019
Background/Aims Few studies have addressed whether there are differences in clinical efficacy between intravenous methylprednisolone (methyl-Pd) and intravenous immunoglobulin (IVIg) use.
Chul Hee Kim   +9 more
doaj   +1 more source

Case report: Subacute combined degeneration of the spinal cord due to nitrous oxide abuse

open access: yesFrontiers in Neurology, 2023
BackgroundNitrous oxide (N2O) is an increasingly popular recreational drug. N2O irreversibly disturbs the metabolism of vitamin B12, resulting in a functional deficiency.
Huijuan Wu   +7 more
doaj   +1 more source

A case of multisystem inflammatory syndrome in children (MIS-C) mimicking Kawasaki disease

open access: yesSri Lanka Journal of Medicine, 2021
Introduction: Severe acute respiratory syndrome coronavirus-2 infection has emerged as a multisystem disorder during the pandemic of Coronavirus disease of 2019 (Covid-19).
M. Rathnayake   +3 more
doaj   +1 more source

Effects of Methylprednisolone on Myocardial Function and Microcirculation in Post-resuscitation: A Rat Model

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundPrevious studies have demonstrated that inflammation and impaired microcirculation are key factors in post-resuscitation syndromes. Here, we investigated whether methylprednisolone (MP) could improve myocardial function and microcirculation by ...
Changsheng Wang   +17 more
doaj   +1 more source

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