Results 61 to 70 of about 81,349 (232)

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Serious Infections in Offspring Exposed to Tumor Necrosis Factor Inhibitors During Pregnancy: Comparison of Timing During Pregnancy and Placental Transfer Ability

Arthritis &Rheumatology, EarlyView.
Objective We evaluated serious infection risk in offspring exposed to tumor necrosis factor inhibitors (TNFi) in utero, separated by TNFi timing and placental transfer ability. Methods Using MarketScan (2011–2021), we identified offspring born to mothers with chronic inflammatory diseases.
Leah K. Flatman, Sasha Bernatsky, Yvan St‐Pierre, Marie‐Eve Beauchamp, Isabelle Malhamé, Anick Bérard, Évelyne Vinet   +6 more
wiley   +1 more source

Use of Corticosteroids in Coronavirus Disease 2019 Pneumonia: A Systematic Review of the Literature

Frontiers in Medicine, 2020
The aim was to investigate the effectiveness of glucocorticoid therapy in patients with COVID-19. A systematic search of the literature across nine databases was conducted from inception until 15th March 2020, following the PRISMA guidelines.
Nicola Veronese, Jacopo Demurtas, Jacopo Demurtas, Lin Yang, Lin Yang, Roberto Tonelli, Roberto Tonelli, Mario Barbagallo, Pierluigi Lopalco, Erik Lagolio, Stefano Celotto, Damiano Pizzol, Liye Zou, Mark A. Tully, Petre Cristian Ilie, Mike Trott, Guillermo F. López-Sánchez, Lee Smith   +17 more
doaj   +1 more source

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

A Case of Cerebral Cortical Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
Sixiao Liu, Kunqian Ji, Wei Wu, Wei Li
wiley   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Silk fibroin‐based biomaterials for spinal cord injury repair: Recent advances and future prospects

BMEMat, EarlyView.
A comprehensive review on the design principles and current strategies of silk fibroin‐based biomaterials in spinal cord injury repair, focusing on environmentally friendly processing techniques, and the strategies for designing composite scaffolds as well as discussing the advantages and current challenges of silk fibroin‐based biomaterials in spinal ...
Xiaoliang Cui, Xuanwen Wang, Siying Liu, Lilei Wang, Menghong Li, Jun Zhang, Li Wang, Ke‐Qin Zhang   +7 more
wiley   +1 more source

Voclosporin‐induced gingival enlargement: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca, Jessica M. Greco, Dimitris N. Tatakis   +2 more
wiley   +1 more source

Efficacy and safety of low dose oral prednisolone as compared to pulse intravenous methylprednisolone in managing moderate severe Graves′ orbitopathy: A randomized controlled trial

Indian Journal of Endocrinology and Metabolism, 2015
Background: High dose oral prednisolone (100 mg/day) in Graves′ orbitopathy (GO) is limited by lesser response, and greater side-effects compared to intravenous (iv) methylprednisolone. Low dose oral prednisolone has not been evaluated in GO.
Ajitesh Roy, Deep Dutta, Sujoy Ghosh, Pradip Mukhopadhyay, Satinath Mukhopadhyay, Subhankar Chowdhury   +5 more
doaj   +1 more source

Predicting epilepsy after new onset refractory status epilepticus due to autoimmune encephalitis: The DAME score

Epilepsia, EarlyView.
Abstract Objective This study aimed to identify risk factors and develop a predictive scoring system for autoimmune‐associated epilepsy in subjects with autoimmune encephalitis presenting with new onset refractory status epilepticus (NORSE). Methods This retrospective, multicenter, cohort study included subjects who presented with NORSE at the onset of
Simona Lattanzi, Sara Matricardi, Alberto Vogrig, Giada Pauletto, Margherita Nosadini, Stefano Sartori, Federico Massa, Luana Benedetti, Stefano Meletti, Francesca Bisulli, Elena Freri, Francesca Felicia Operto, Silvia Bozzetti, Sara Mariotto, Simone Beretta, Eleonora Rosati, Elisabetta Cesaroni, Carla Marini, Tiziana Granata, Flavio Villani, Immune Epilepsies Study Group of the Italian League Against Epilepsy, Ruggero Bernabei, Stefania Maria Bova, Silva Cappanera, Luigi Caputi, Edward Cesnik, Francesco Deleo, Lidia Di Vito, Giuseppe D’Orsi, Giovanni Falcicchio, Elisa Fallica, Edoardo Ferlazzo, Lucia Fusco, Matteo Gastaldi, Giada Giovannini, Angela La Neve, Claudio Liguori, Pietro Mattioli, Lorenzo Muccioli, Carlotta Mutti, Angelo Pascarella, Elena Pasini, Daniela Passarelli, Francesca Ragona, Romana Rizzi, Elena Tartara, Valentina Tontini, Alberto Verrotti, Federica Zibordi, Lucia Zinno, Antonio Zito   +50 more
wiley   +1 more source