Results 61 to 70 of about 84,477 (249)

Impact of cumulative glucocorticoid exposure on vancomycin clearance in hospitalized children: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Prior glucocorticoid exposure is associated with modestly increased vancomycin clearance in hospitalized children, partly mediated by renal function and inflammation and may contribute to subtherapeutic early drug exposure. Abstract Introduction Augmented renal clearance (ARC) can lead to subtherapeutic vancomycin exposure in children.
Kouki Tomari, Ruud H. J. Verstegen, Cintia Cruz, Erin Chung, Aleena Azim, Shinya Ito, Tamorah R. Lewis   +6 more
wiley   +1 more source

Use of Corticosteroids in Coronavirus Disease 2019 Pneumonia: A Systematic Review of the Literature

Frontiers in Medicine, 2020
The aim was to investigate the effectiveness of glucocorticoid therapy in patients with COVID-19. A systematic search of the literature across nine databases was conducted from inception until 15th March 2020, following the PRISMA guidelines.
Nicola Veronese, Jacopo Demurtas, Jacopo Demurtas, Lin Yang, Lin Yang, Roberto Tonelli, Roberto Tonelli, Mario Barbagallo, Pierluigi Lopalco, Erik Lagolio, Stefano Celotto, Damiano Pizzol, Liye Zou, Mark A. Tully, Petre Cristian Ilie, Mike Trott, Guillermo F. López-Sánchez, Lee Smith   +17 more
doaj   +1 more source

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

British Journal of Clinical Pharmacology, EarlyView.
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen, Patrick C. Souverein, Eibert R. Heerdink, Elisabeth Y. Bijlsma, Lucianne Groenink   +4 more
wiley   +1 more source

A Selectfluor‐based Polonovski Rearrangement Leading to Novel Entities for Synthetic and Medicinal Applications

Chemistry – A European Journal, EarlyView.
Starting from carboxylic acids and Selectfluor‐derivatives, functionalized diazabicyclooctanes can be obtained via a novel Polonovski‐type rearrangement proceeding under mild reaction conditions. Besides their use in organic synthesis the unique structure and reactivity of the rearrangement products enables applications in medicinal chemistry ...
Jakob Kuhn, Susanne Gradl, Vanessa Osterloh, Peter Gmeiner, Harald Hübner, Markus R. Heinrich   +5 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Human Metapneumovirus and Its Association With Otorhinolaryngological Manifestations: A Systematic Review With Descriptive Synthesis

Eye &ENT Research, EarlyView.
ABSTRACT Human metapneumovirus (HMPV) is a respiratory virus that predominantly affects the pediatric population. Its role as an infective agent in ear, nose, and throat (ENT) diseases is not yet well understood. To systematically review the available literature on the association between HMPV and ENT manifestations, following PRISMA guidelines, a ...
Ali Gohar, Muhammad Husnain Ahmad, Hamza Zaheer, Fizza Inam, Moeez Ahmad Saeed, Nimra Mehmood, Abdul Rehman Shahid Khan, Alishbah Saeed, Hanzala Zahid, Yashika Gupta, Muhammad Bilal Akram, Habban Ghani, Muhammad Ahmad Farooq   +12 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Cenobamate use in super‐refractory status epilepticus: A report of three cases

Epileptic Disorders, EarlyView.
Abstract Objectives Super‐refractory status epilepticus (SRSE) is a neurological emergency with high morbidity and mortality. Cenobamate, a novel antiseizure medication, may be helpful in managing SRSE, but evidence is limited. Methods This retrospective case series reports the use of cenobamate as add‐on therapy in the management of three cases of ...
Marina Romozzi, Juan Luis Alcala‐Zermeno, Antonio Funcis, Federico Tosto, Marta Piccioli, Luigi Francesco Iannone, Riccardo Maviglia, Masahito Katsuki, Yasuhiko Matsumori, Paolo Calabresi, Raffaele Iorio, Catello Vollono   +11 more
wiley   +1 more source

Efficacy and safety of low dose oral prednisolone as compared to pulse intravenous methylprednisolone in managing moderate severe Graves′ orbitopathy: A randomized controlled trial

Indian Journal of Endocrinology and Metabolism, 2015
Background: High dose oral prednisolone (100 mg/day) in Graves′ orbitopathy (GO) is limited by lesser response, and greater side-effects compared to intravenous (iv) methylprednisolone. Low dose oral prednisolone has not been evaluated in GO.
Ajitesh Roy, Deep Dutta, Sujoy Ghosh, Pradip Mukhopadhyay, Satinath Mukhopadhyay, Subhankar Chowdhury   +5 more
doaj   +1 more source

Methylprednisolone [PDF]

Reactions Weekly, 2021
  +4 more sources