Results 281 to 290 of about 365,379 (338)

Molecular Mechanism of the IRF1/NFE2L1‐DT/ALKBH5/Cx43 Axis in Radiation‐Induced Injury in Vascular Endothelial Cells Through Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radiotherapy.
Chen Li, Jia‐Wen Yang, Yong‐Rui Jia, Jie Zhang, Qiao Gou   +4 more
wiley   +1 more source

A proof-of-concept study: investigating the impact of COMT genotype and proline on negative symptoms in Alzheimer's disease. [PDF]

BJPsych Open
Clelland JD, Cure HW, Canizares AM, Anderson JH, Rawal B, Wong SA, Kerner N, Huey ED, Honig LS, Devanand DP, Clelland CL.   +10 more
europepmc   +1 more source

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

The Putative RNA Methyltransferase Modulates T3SS Expression and Host NF-κB Activation via T6SS-Mediated Translocation in <i>Pseudomonas aeruginosa</i>. [PDF]

Int J Mol Sci
An Y, Lee Y, Jin Y, Wu W, Ha UH.
europepmc   +1 more source

Recent Advancements in the Characterization of D‐Amino Acid and Isoaspartate Post‐Translational Modifications

Mass Spectrometry Reviews, EarlyView.
ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley   +1 more source

Neurochemical metabolic pathways display regional and age-specific expression patterns in the chicken intestinal tract. [PDF]

Poult Sci
Wickramasuriya SS, Lyte JM.
europepmc   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

The Regulatory Role of m⁶A Modification in the Function and Signaling Pathways of Animal Stem Cells. [PDF]

Cells
Yang X, Xu Y, Zhu S, Wang M, Cao H, Lu L.   +5 more
europepmc   +1 more source

DNA methyltransferase Dnmt3ba-mediated epigenetic modulation of Integrin signaling is essential for hematopoietic stem and progenitor cell development. [PDF]

Commun Biol
Ai K, Wu Y, Liang G, Kong H, Yang X, Li N, Liu Z, Dong Y, Xu J, Zhang L, Chen X, Fu Y, Wang L, Li L.   +13 more
europepmc   +1 more source

Tangerine : a Starship -like element in the genomes of Xanthoria lichen-forming fungi

Tagirdzhanova G, Bucknell A, Cameron ES, Finn RD, Blaxter M, McDonald MC, Talbot NJ.   +6 more
europepmc   +1 more source