Localization and synthesis of prenylquinones in isolated outer and inner envelope membranes from spinach chloroplasts [PDF]
, 1985 The prenylquinone content and biosynthetic capabilities of membrane fractions enriched in outer and inner envelope membranes from spinach chloroplasts were analyzed.
Bligh +23 more
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Abnormality of m6A mRNA Methylation Is Involved in Alzheimer’s Disease
Frontiers in Neuroscience, 2020 Alzheimer’s disease (AD), the most common form of dementia, is highly prevalent in older adults. The main clinical feature is the progressive decline of memory function, which eventually leads to the decline of cognitive function.
Min Han +7 more
doaj +1 more source
Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals. [PDF]
, 2016 IFIT (interferon-induced with tetratricopeptide repeats) proteins are critical mediators of mammalian innate antiviral immunity. Mouse IFIT1 selectively inhibits viruses that lack 2'O-methylation of their mRNA 5' caps.
Daugherty, Matthew D +3 more
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Exploring the Phytochemical Landscape of the Early-Diverging Flowering Plant Amborella trichopoda Baill. [PDF]
, 2019 Although the evolutionary significance of the early-diverging flowering plant Amborella (Amborella trichopoda Baill.) is widely recognized, its metabolic landscape, particularly specialized metabolites, is currently underexplored.
Chang, Lijing +3 more
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Does the catechol-O-methyltransferase (COMT) Val158Met human polymorphism in influence procrastination? [PDF]
, 2017 Genetic studies are enlightening how the expression of several genes influences neuronal activity and all facets of human normal and abnormal behaviour. Among these, a growing body of information shows that a few key genes regulating activity of central ...
Abate, Georgia +3 more
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Frontiers in Microbiology, 2017 Despite the persistent and costly problem caused by (bacterio)phage predation of Streptococcus thermophilus in dairy plants, DNA sequence information relating to these phages remains limited.
Brian McDonnell +10 more
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Frontiers in Plant Science, 2023 Amaranth has become increasingly popular due to its highly nutritious grains and ability to tolerate environmental stress. The mechanism underlying defense and adaptation to environmental stress is a complicated process involving DNA methylation and ...
Veronika Lancíková +2 more
doaj +1 more source
Functional Crosstalk between Lysine Methyltransferases on Histone Substrates: The Case of G9A/GLP and Polycomb Repressive Complex 2 [PDF]
, 2015 Significance: Methylation of histone H3 on lysine 9 and 27 (H3K9 and H3K27) are two epigenetic modifications that have been linked to several crucial biological processes, among which are transcriptional silencing and cell differentiation.
Ait Si Ali, Slimane +2 more
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Clinical and Biological Significances of a Methyltransferase-Related Signature in Diffuse Glioma
Frontiers in Oncology, 2020 Methylation of DNA, RNA or protein is a reversible modification. The proteins and genes that regulate this modification can be a candidate target for tumor therapy. However, the characteristics of methyltransferase related genes in glioma remain obscure.
Ying Zhang +11 more
doaj +1 more source
DNMT3B in vitro knocking-down is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation [PDF]
, 2016 Aberrant DNA methylation has been frequently observed in many human cancers, including rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children.
Camero, Simona +11 more
core +1 more source