Results 31 to 40 of about 58,830 (269)
Females present a higher risk of adverse drug reactions. Sex‐related differences in drug concentrations may contribute to these observations but they remain understudied given the underrepresentation of females in clinical trials.
Jessica Hindi +13 more
doaj +1 more source
Β-blockers treatment of cardiac surgery patients enhances isolation and improves phenotype of cardiosphere-derived cells [PDF]
Β-blockers (BB) are a primary treatment for chronic heart disease (CHD), resulting in prognostic and symptomatic benefits. Cardiac cell therapy represents a promising regenerative treatment and, for autologous cell therapy, the patients clinical history ...
ANGELINI, FRANCESCO +11 more
core +1 more source
Effects of Metoprolol and Nebivolol on Exercise Blood Pressure in Patients with Mild Hypertension
Objectives. We planned to compare the impact of two beta blockers, metoprolol and nebivolol, on arterial blood pressure during exercise in patients with mild hypertension. Methods.
Huseyin Ugur Yazici +3 more
doaj +1 more source
WHAT DOES PROVIDE A CLINICAL EFFICACY OF METOPROLOL?
Relationship of metoprolol clinical efficacy with its different salts (tartrate, succinate, fumarate) as well as its presentations (tablets with immediate, controlled or sustained release) is analyzed.
E. V. Kuleshova
doaj +1 more source
Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure. [PDF]
BACKGROUND: Moderate and moderately severe renal impairment are common in patients with heart failure and reduced ejection fraction, but whether beta-blockers are effective is unclear, leading to underuse of life-saving therapy.
Andersson, B +22 more
core +8 more sources
Effect on Mortality of Higher Versus Lower β-Blocker (Metoprolol Succinate or Carvedilol) Dose in Patients With Heart Failure [PDF]
This study aimed to compare the effect of β-blocker dose and heart rate (HR) on mortality in patients with heart failure with reduced ejection fraction (HFrEF).
Ajam, Samer +4 more
core +1 more source
Plasma C-type natriuretic peptide as a predictor for therapeutic response to metoprolol in children with postural tachycardia syndrome. [PDF]
POTS is a global public-health disease, but predictor for therapeutic response to metoprolol in children with POTS is lacking. This study was designed to investigate predictive value of plasma C-type natriuretic peptide (CNP) in the therapeutic efficacy ...
Jing Lin +9 more
doaj +1 more source
Hyperglycemia-induced impairment of the blood-retinal barrier represents the main pathological event in diabetic retinopathy that is elicited by a reduced cellular response to an accumulation of reactive oxygen species (ROS) and increased inflammation ...
Giovanni Giurdanella +9 more
doaj +1 more source
Objective High blood pressure is one of the most important risk factors, directly responsible for increasing the cardiovascular morbidity and mortality. The primary objective was to evaluate the efficacy of metoprolol XL/chlorthalidone against metoprolol
Pareek A +4 more
doaj +1 more source
Carvedilol and metoprolol are both able to preserve myocardial function in type 2 diabetes
Purpose Increasing cohorts of patients present with diabetic cardiomyopathy, and with no targeted options, treatment often rely on generic pharmaceuticals such as β‐blockers. β‐blocker efficacy is heterogenous, with second generation β‐blocker metoprolol
Carol T. Bussey +6 more
doaj +1 more source

