Results 31 to 40 of about 58,830 (269)

Females present higher dose‐adjusted drug concentrations of metoprolol and allopurinol/oxypurinol than males

open access: yesClinical and Translational Science, 2023
Females present a higher risk of adverse drug reactions. Sex‐related differences in drug concentrations may contribute to these observations but they remain understudied given the underrepresentation of females in clinical trials.
Jessica Hindi   +13 more
doaj   +1 more source

Β-blockers treatment of cardiac surgery patients enhances isolation and improves phenotype of cardiosphere-derived cells [PDF]

open access: yes, 2016
Β-blockers (BB) are a primary treatment for chronic heart disease (CHD), resulting in prognostic and symptomatic benefits. Cardiac cell therapy represents a promising regenerative treatment and, for autologous cell therapy, the patients clinical history ...
ANGELINI, FRANCESCO   +11 more
core   +1 more source

Effects of Metoprolol and Nebivolol on Exercise Blood Pressure in Patients with Mild Hypertension

open access: yesThe Scientific World Journal, 2013
Objectives. We planned to compare the impact of two beta blockers, metoprolol and nebivolol, on arterial blood pressure during exercise in patients with mild hypertension. Methods.
Huseyin Ugur Yazici   +3 more
doaj   +1 more source

WHAT DOES PROVIDE A CLINICAL EFFICACY OF METOPROLOL?

open access: yesРациональная фармакотерапия в кардиологии, 2016
Relationship of metoprolol clinical efficacy with its different salts (tartrate, succinate, fumarate) as well as its presentations (tablets with immediate, controlled or sustained release) is analyzed.
E. V. Kuleshova
doaj   +1 more source

Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure. [PDF]

open access: yes, 2019
BACKGROUND: Moderate and moderately severe renal impairment are common in patients with heart failure and reduced ejection fraction, but whether beta-blockers are effective is unclear, leading to underuse of life-saving therapy.
Andersson, B   +22 more
core   +8 more sources

Effect on Mortality of Higher Versus Lower β-Blocker (Metoprolol Succinate or Carvedilol) Dose in Patients With Heart Failure [PDF]

open access: yes, 2018
This study aimed to compare the effect of β-blocker dose and heart rate (HR) on mortality in patients with heart failure with reduced ejection fraction (HFrEF).
Ajam, Samer   +4 more
core   +1 more source

Plasma C-type natriuretic peptide as a predictor for therapeutic response to metoprolol in children with postural tachycardia syndrome. [PDF]

open access: yesPLoS ONE, 2015
POTS is a global public-health disease, but predictor for therapeutic response to metoprolol in children with POTS is lacking. This study was designed to investigate predictive value of plasma C-type natriuretic peptide (CNP) in the therapeutic efficacy ...
Jing Lin   +9 more
doaj   +1 more source

The Anti-Inflammatory Effect of the β1-Adrenergic Receptor Antagonist Metoprolol on High Glucose Treated Human Microvascular Retinal Endothelial Cells

open access: yesCells, 2021
Hyperglycemia-induced impairment of the blood-retinal barrier represents the main pathological event in diabetic retinopathy that is elicited by a reduced cellular response to an accumulation of reactive oxygen species (ROS) and increased inflammation ...
Giovanni Giurdanella   +9 more
doaj   +1 more source

Antihypertensive efficacy of metoprolol XL/Low dose chlorthalidone (6.25 mg) combination: a randomized, comparative study in Indian patients with mild-to-moderate essential hypertension

open access: yesEuropean Journal of Medical Research, 2009
Objective High blood pressure is one of the most important risk factors, directly responsible for increasing the cardiovascular morbidity and mortality. The primary objective was to evaluate the efficacy of metoprolol XL/chlorthalidone against metoprolol
Pareek A   +4 more
doaj   +1 more source

Carvedilol and metoprolol are both able to preserve myocardial function in type 2 diabetes

open access: yesPhysiological Reports, 2020
Purpose Increasing cohorts of patients present with diabetic cardiomyopathy, and with no targeted options, treatment often rely on generic pharmaceuticals such as β‐blockers. β‐blocker efficacy is heterogenous, with second generation β‐blocker metoprolol
Carol T. Bussey   +6 more
doaj   +1 more source

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