Results 111 to 120 of about 4,331 (257)
Characterizations of Metric-Dependent Dimension Functions [PDF]
James C. Smith
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This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
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Dimension of metric spaces and Hilbert’s problem 13 [PDF]
Phillip A. Ostrand
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Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
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A note on countable-dimensional metric spaces [PDF]
Keiô Nagami, J. H. Roberts
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Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
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Metric dimension of generalized wheels
In a graph G, a vertex w∈V(G)resolves a pair of vertices u,v∈V(G)if d(u,w)≠d(v,w). A resolving set of G is a set of vertices S such that every pair of distinct vertices in V(G)is resolved by some vertex in S.
Badekara Sooryanarayana+2 more
doaj
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
On the parallelisability under Riemannian metrics of direction fields over $3$-dimensional manifolds, II [PDF]
Shōbin Kashiwabara
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