Results 81 to 90 of about 282,648 (277)
A remark on positive topological entropy of N-buffer switched flow networks
We present a simpler elementary proof on positive topological entropy of the N-buffer switched flow networks based on a new simple theorem on positive topological entropy of continuous map on compact metric space.
Xiao-Song Yang
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Large Alphabets and Incompressibility
We briefly survey some concepts related to empirical entropy -- normal numbers, de Bruijn sequences and Markov processes -- and investigate how well it approximates Kolmogorov complexity. Our results suggest $\ell$th-order empirical entropy stops being a
Becher +21 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Algorithm for Efficient Entropy Estimation
We consider the problem of the nonparametric entropy estimation of a stationary ergodic process. Our approach is based on the nearest-neighbor distances. We propose a broad class of metrics on the space Ω = AN of right-sided infinite sequences drawn from
E. A. Timofeev
doaj +3 more sources
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Corrections to de Sitter entropy through holography
The holographic entanglement entropy is computed for an entangling surface that coincides with the horizon of a boundary de Sitter metric. This is achieved through an appropriate slicing of anti-de Sitter space and the implementation of a UV cutoff.
N. Tetradis
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source

