Results 91 to 100 of about 642,101 (319)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Rectangular cone b-metric spaces over Banach algebra and contraction principle

open access: yesFixed Point Theory and Applications, 2017
Rectangular cone b-metric spaces over a Banach algebra are introduced as a generalization of metric space and many of its generalizations. Some fixed point theorems are proved in this space and proper examples are provided to establish the validity and ...
Reny George   +4 more
doaj   +1 more source

Frames for Metric Spaces [PDF]

open access: yesarXiv, 2020
We make a systematic study of frames for metric spaces. We prove that every separable metric space admits a metric $\mathcal{M}_d$-frame. Through Lipschitz-free Banach spaces we show that there is a correspondence between frames for metric spaces and frames for subsets of Banach spaces. We derive some characterizations of metric frames.
arxiv  

On partial metric spaces and partial cone metric spaces

open access: yesHacettepe Journal of Mathematics and Statistics, 2017
It this article we shall show that partial metric spaces and partial cone metric spaces are quasi-uniformizable and hence quasi-metrizable. Finally, an application to the Banach’s fixed point theorem will be presented in this context.
openaire   +3 more sources

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Tangent spaces to metric spaces and to their subspaces [PDF]

open access: yesarXiv, 2009
We investigate a tangent space at a point of a general metric space and metric space valued derivatives. The conditions under which two different subspace of a metric space have isometric tangent spaces in a common point of these subspaces are completely determinated.
arxiv  

The metric of colour space [PDF]

open access: yesGraphical Models, 2015
Display Omitted The space of colours is a fascinating space. It is a real vector space, but no matter what inner product you put on the space the resulting Euclidean distance does not correspond to human perception of difference between colours.In 1942 MacAdam performed the first experiments on colour matching and found the MacAdam ellipses which are ...
openaire   +3 more sources

On Type of Metric Spaces [PDF]

open access: yesTransactions of the American Mathematical Society, 1986
Families of finite metric spaces are investigated. A notion of metric type is introduced and it is shown that for Banach spaces it is consistent with the standard notion of type. A theorem parallel to the Maurey-Pisier Theorem in Local Theory is proved. Embeddings of l p {l_p} -cubes into the
Haim J. Wolfson   +2 more
openaire   +2 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

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