Results 81 to 90 of about 202,228 (310)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Fixed point theorems in a new type of modular metric spaces

open access: yesFixed Point Theory and Applications, 2018
In this paper, considering both a modular metric space and a generalized metric space in the sense of Jleli and Samet (Fixed Point Theory Appl. 2015:61, 2015), we introduce a new concept of generalized modular metric space.
Duran Turkoglu, Nesrin Manav
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Related fixed point theorems on two complete and compact metric spaces

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1998
A new related fixed point theorem on two complete metric spaces is obtained. A generalization is given for two compact metric spaces.
R. K. Namdeo   +3 more
doaj   +1 more source

Rectangular cone b-metric spaces over Banach algebra and contraction principle

open access: yesFixed Point Theory and Applications, 2017
Rectangular cone b-metric spaces over a Banach algebra are introduced as a generalization of metric space and many of its generalizations. Some fixed point theorems are proved in this space and proper examples are provided to establish the validity and ...
Reny George   +4 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy