Results 101 to 110 of about 67,599 (265)

A characterization of hyperbolic spaces

open access: yes, 2006
We show that a geodesic metric space, and in particular the Cayley graph of a finitely generated group, is hyperbolic in the sense of Gromov if and only if intersections of any two metric balls balls is itself "almost" a metric ball.
Chatterji, Indira, Niblo, Graham A.
core  

An introduction to Smarandache multi-spaces and mathematical combinatorics [PDF]

open access: yes, 2007
These Smarandache spaces are right theories for objectives by logic. However, the mathematical combinatorics is a combinatorial theory for branches in classical mathematics motivated by a combinatorial speculation.
Linfan Mao, Mao. Linfan
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The topology of partial metric spaces [PDF]

open access: yes
The T0 world of Scott's topological models used in the denotational semantics of programming languages may at first sight appear to have nothing whatever in common with the Hausdorff world of metric space theory.
Matthews, Stephen G.
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Remarks on Some Recent Fixed Point Results on Quaternion-Valued Metric Spaces

open access: yesAbstract and Applied Analysis, 2014
Very recently, Ahmed et al. introduced the notion of quaternion-valued metric as a generalization of metric and proved a common fixed point theorem in the context of quaternion-valued metric space.
Ravi P. Agarwal   +3 more
doaj   +1 more source

Metric Sobolev spaces [PDF]

open access: yes, 2002
summary:We describe an approach to establish a theory of metric Sobolev spaces based on Lipschitz functions and their pointwise Lipschitz constants and the Poincaré ...
Koskela, Pekka
core  

Lipschitz-type functions on metric spaces

open access: yes, 2008
In order to find metric spaces X for which the algebra Lip∗(X) of bounded Lipschitz functions on X determines the Lipschitz structure of X, we introduce the class of small-determined spaces.
Jaramillo, Jesús A.   +3 more
core   +1 more source

Estimating the weight of metric minimum spanning trees in sublinear time [PDF]

open access: yes, 2008
In this paper we present a sublinear-time $(1+\varepsilon)$-approximation randomized algorithm to estimate the weight of the minimum spanning tree of an $n$-point metric space. The running time of the algorithm is $\widetilde{\mathcal{O}}(n/\varepsilon^{\
Christian Sohler   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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