Results 91 to 100 of about 45,851 (264)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Multiplicative modular metric spaces and some fixed point results

Journal of Inequalities and Applications
This study aims to introduce a novel type of metric, defined as the w-multiplicative modular metric space, which becomes an expanded idea that includes two metric spaces. We present and demonstrate some of this new space’s topological properties. We also
Elif Kaplan, Nihal Taş, Salma Haque, Nabil Mlaiki   +3 more
doaj   +1 more source

On a Theorem in Metric Spaces

The Annals of Mathematical Statistics, 1958
\(P\) sei die folgende Abschwächung der Kontinuumshypothese: Die Mächtigkeit der Gesamtheit der Untermengen einer überabzählbaren Grundmenge ist größer als die des Kontinuums. Mit \(P\) als äquivalent erweist sich die folgende Aussage: Der metrische Raum \(X\) ist dann und nur dann separabel, wenn die Mächtigkeit der Gesamtheit seiner Borelschen Mengen
Varadarajan, V. S., Rao, R. Ranga
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Remarks on Some Recent Fixed Point Results on Quaternion-Valued Metric Spaces

Abstract and Applied Analysis, 2014
Very recently, Ahmed et al. introduced the notion of quaternion-valued metric as a generalization of metric and proved a common fixed point theorem in the context of quaternion-valued metric space.
Ravi P. Agarwal, Hamed H. Alsulami, Erdal Karapınar, Farshid Khojasteh   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Separability of Metric Spaces [PDF]

Transactions of the American Mathematical Society, 1970
A topological space S is separable means that some countable subset of S is dense in S. A subset T of a topological space is separable means that T has a countable subset which is dense in T. In view of the importance of this property, it is natural to inquire about conditions under which a space is separable.
openaire   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Metric spaces are Ramsey

European Journal of Combinatorics, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources