Results 91 to 100 of about 5,269,237 (355)
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Some Properties of C ∗ -Graded Metric Spaces and Fixed Point Results
Journal of Mathematical Extension, 2010 In this paper, by using of C ∗ -algebra we give a metric with range in positive unit ball of a C ∗ -algebra. Indeed this is a generalization of a fuzzy metric space.
Sh. Sedghi∗, A. Gilani, M. Foozooni
doaj
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
REMATThis study aims to analyze parabolas in the two dimensional unit disk equipped with a Funk metric. The analysis leads to four types of parabolas are obtained, due to the non-reversibility of the Funk metric.
Newton Mayer Solórzano Chávez +2 more
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Scientific and Practical Metric Units [PDF]
Nature, 1919 IN the article entitled “Scientific and Practical Metric Units” which appeared in NATURE of October 24, 1918, reference is made to the convenient bridge to the metric system which exists in the ton, and the author asks for a convenient monosyllabic name for a weight of about 2.2 lb. I would commend for consideration the word “seer.” The Imperial Indian
openaire +2 more sources
Visualizing the Unit Ball for the Teichmüller Metric [PDF]
Experimental Mathematics, 2016 We describe a method to compute the norm on the cotangent space to the moduli space of Riemann surfaces associated to the Finsler Teichm ller metric. Our method involves computing the periods of abelian double covers and is easy to implement for Riemann surfaces presented as algebraic curves using existing tools for approximating period matrices of ...
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Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source