Results 91 to 100 of about 2,231,192 (331)
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
, 2006 In the context of the Semantic Web, many ontology-related operations, e.g. ontology ranking, segmentation, alignment, articulation, reuse, evaluation, can be boiled down to one fundamental operation: computing the similarity and?or dissimilarity among ontological entities, and in some cases among ontologies themselves. In this paper, we review standard
Hu, Bo +5 more
openaire +3 more sources
Constant Scalar Curvature Metrics on Boundary Complexes of Cyclic Polytopes [PDF]
, 2010 In [7], a notion of constant scalar curvature metrics on piecewise flat manifolds is defined. Such metrics are candidates for canonical metrics on discrete manifolds. In this paper, we define a class of vertex transitive metrics on certain triangulations
Champion, Daniel +3 more
core
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
Generalizations of metrics and partial metrics
Hacettepe Journal of Mathematics and Statistics, 2017 In [14] $k$-metric spaces were defined for certain $\ell$-group applications, by weakening the metric triangle inequality. In this article we show that much of the theory of metric spaces, including the Banach fixed point theorem extends to these spaces.
KOPPERMAN, Ralph, PAJOOHESH, Homeira
openaire +4 more sources
BMC Medicine, 2018 Background The host, microbial, and environmental factors that contribute to variation in tuberculosis (TB) disease are incompletely understood. Accumulating evidence suggests that one driver of geographic variation in TB disease is the local ecology of ...
Kirsten E Wiens +16 more
doaj +1 more source
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
On the extension of a partial metric to a tree metric
Discrete Mathematics, 2004 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Guénoche, Alain +2 more
openaire +4 more sources