Results 21 to 30 of about 74,689 (274)
Building Artificial Neural Networks for the Optimization of Sustained-Release Kinetics of Metronidazole from Colonic Hydrophilic Matrices. [PDF]
PharmaceuticsMaderuelo C +2 more
europepmc +3 more sources
Advanced Healthcare Materials, EarlyView.A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji +8 more
wiley +1 more source
Metronidazole-induced neurotoxicity: Is iron a contributing factor?
Mediterranean Journal of Pharmacy and Pharmaceutical SciencesMetronidazole-induced neurotoxicity is a rising challenge in managing susceptible infections. The mechanisms involved in metronidazole-induced neurotoxicity are not fully unraveled.
Moses W. Bariweni
doaj +1 more source
Metronidazole-induced encephalopathy in a patient with infectious colitis: a case report
Journal of Medical Case Reports, 2011 Introduction Encephalopathy is a rare disease caused by adverse effects of antibiotic drugs such as metronidazole. The incidence of metronidazole-induced encephalopathy is unknown, although several previous studies have addressed metronidazole ...
Park Ik +4 more
doaj +1 more source
Children, 2022 Metronidazole-induced encephalopathy (MIE) is a rare and unpredictable complication that is most commonly reported in adults. Here, we present the case of MIE in a patient treated with rectal, oral, and intravenous metronidazole.
Karolina Rybak +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery +10 more
wiley +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Bioadhesive Controlled Metronidazole Release Matrix Based on Chitosan and Xanthan Gum
Marine Drugs, 2010 Metronidazole, a common antibacterial drug, was incorporated into a hydrophilic polymer matrix composed of chitosan xanthan gum mixture. Hydrogel formation of this binary chitosan-xanthan gum combination was tested for its ability to control the release ...
Ala’a F. Eftaiha +6 more
doaj +1 more source
METRONIDAZOLE GEL EFFECT ON RATS WITH BACTERIA-INDUCED PERIODONTITIS
ODONTO: Dental Journal, 2020 Background: Periodontitis is an inflammatory disease in the periodontal tissue and causes progressive tissue damage. Tissue Inhibitor of Matrix Metalloproteinases-1 (TIMP-1) is directly responsible for the pathogenesis of periodontal diseases.
Muhamat Muhtar S. Abdurrohman +1 more
doaj +1 more source
Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays
Advanced Sensor Research, EarlyView.This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley +1 more source