Results 41 to 50 of about 596,809 (161)

METRONIDAZOLE GEL EFFECT ON RATS WITH BACTERIA-INDUCED PERIODONTITIS [PDF]

, 2020
Background: Periodontitis is an inflammatory disease in the periodontal tissue and causes progressive tissue damage. Tissue Inhibitor of Matrix Metalloproteinases-1 (TIMP-1) is directly responsible for the pathogenesis of periodontal diseases.
Putranto, R. Rama, Abdurrohman, Muhamat Muhtar S.   +1 more
core   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, Volume 40, Issue 16, August 2026.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source

Phase I Randomised Clinical Trial of an HIV-1(CN54), Clade C, Trimeric Envelope Vaccine Candidate Delivered Vaginally. [PDF]

, 2011
We conducted a phase 1 double-blind randomised controlled trial (RCT) of a HIV-1 envelope protein (CN54 gp140) candidate vaccine delivered vaginally to assess immunogenicity and safety.
Fraser Carol A., Wiggins, RC, Cai Chun, David J Lewis, David J. Lewis, Maria Woodrow, Martin P. Cranage, Manoussaka, Maria, Wiggins Rebecca C., Giemza, Rafaela, Giemza Rafaela, Fraser, CA, Alethea Cope, Cai, Chun, Lacey, Charles J, Cranage Martin P., Cai, C, Cope Alethea, Abdel N Mahmoud, Cope, A, Tom Cole, Robin J Shattock, Jeffs, Simon A, Shattock, RJ, Rebecca C. Wiggins, Maria Manoussaka, Charles J Lacey, Charles J. Lacey, Manoussaka Maria, Cranage, Martin P, Cole Tom, Martin P Cranage, Lewis David J., Shattock, Robin J, Lacey, CJ, Jeffs Simon A., Woodrow, M, Manoussaka, M, Lewis, David J, Rafaela Giemza, Chun Cai, Mahmoud Abdel N., Robin J. Shattock, Wiggins, Rebecca C, Cole, Tom, Simon A. Jeffs, Shattock Robin J., Fraser, Carol A, Mahmoud, AN, Simon A Jeffs, Lewis, DJ, Giemza, R, Carol A Fraser, Woodrow, Maria, Jeffs, SA, Carol A. Fraser, Woodrow Maria, Cole, T, Cope, Alethea, Abdel N. Mahmoud, Mahmoud, Abdel N, Rebecca C Wiggins, Cranage, MP, Lacey Charles J.   +63 more
core   +2 more sources

Acceptability of and treatment preferences for recurrent bacterial vaginosis-Topical lactic acid gel or oral metronidazole antibiotic: Qualitative findings from the VITA trial.

PLoS ONE, 2019
BackgroundBacterial vaginosis (BV) is associated with an elevated vaginal pH and the presence of abnormal offensive discharge. It is common, often recurrent, and the most effective treatment regimen is unknown.
Jocelyn Anstey Watkins, Jonathan D C Ross, Sukhwinder Thandi, Clare Brittain, Joe Kai, Frances Griffiths   +5 more
doaj   +1 more source

Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective

VIEW Medicine, Volume 1, Issue 1, August 2026.
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng, Qing Cong, Ling Lin, Liang Qiao   +3 more
wiley   +1 more source

Association of Atopobium vaginae, a recently described metronidazole resistant anaerobe, with bacterial vaginosis

BMC Infectious Diseases, 2004
Background Bacterial vaginosis (BV) is a polymicrobial syndrome characterized by a change in vaginal flora away from predominantly Lactobacillus species. The cause of BV is unknown, but the condition has been implicated in diverse medical outcomes.
Fortenberry J Dennis, Aldridge Kenneth E, Masztal Alicia, Ferris Michael J, Fidel Paul L, Martin David H   +5 more
doaj   +1 more source

ANALYSIS OF THE EFFECTIVENESS OF TREATMENT OF BACTERIAL VAGINOSIS WITH INTRAVAGINAL DRUGS

Мать и дитя в Кузбассе, 2022
The aim of the study was to improve the results of treatment of women of reproductive age with bacterial vaginosis. Currently, the question of effective therapy of bacterial vaginosis remains open. A variety of treatment regimens for bacterial vaginosis
Ульяна Владимировна Пилецкая, Константин Юрьевич Макаров, Татьяна Михайловна Соколова, Татьяна Александровна Дробышева, Зульфия Базарбековна Хаятова, Татьяна Вячеславовна Киселева   +5 more
doaj  

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma, Jiahui Huang, Yitong Chen, Haoxuan Wang, Hang Zou, Wanghong Zhao, Zilong Deng   +6 more
wiley   +1 more source

Acceptability and use of the diaphragm and Replens lubricant gel for HIV prevention in Southern Africa. [PDF]

, 2009
The acceptability and use of the diaphragm and lubricant gel were assessed as part of a large randomized controlled trial to determine the effectiveness of the methods in women's HIV acquisition.
Ramjee, Gita, Nkala, Busisiwe, Chidanyika, Agnes C., Padian, Nancy S, Elizabeth T. Montgomery, Blanchard, Kelly, Straten, Ariane, Agnes C. Chidanyika, van der Straten, Ariane, Naomi Lince, Padian, Nancy S., Montgomery, Elizabeth T, Chidanyika, Agnes C, null null, Busisiwe Nkala, Kelly Blanchard, Ariane van der Straten, Nancy S. Padian, Helen Cheng, MIRA team, Montgomery, Elizabeth T., Lince, Naomi, Gita Ramjee, Cheng, Helen   +23 more
core   +1 more source

BACTERIAL VAGINOSIS; COMPARISON BETWEEN METRONIDAZOLE VAGINAL GEL AND CLINDAMYCIN VAGINAL CREAM FOR TREATMENT OF BACTERIAL VAGINOSIS

THE PROFESSIONAL MEDICAL JOURNAL, 2017
In women of reproductive age bacterial vaginosis is a most common polymicrobialdisease and is the leading reason for vaginal discharge in this age group. Additionally itis further linked with sizeable disease burden of community problem in terms of infectiouscomplications.
Faiqa Saleem, Munazza Malik, Muhammad Sohaib Shahid, Muhammad Tayyab   +3 more
openaire   +2 more sources