Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate. [PDF]
Exp Ther Med, 2020 Li M +7 more
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Periodic fever and mevalonate kinase deficiency
, 2002 Mevalonate kinase (MK) deficiency is an autosomal recessive disorder, caused by mutations in the MVK-gene on chromosome 12q24. The affected enzyme catalyzes an early step in isoprenoid biosynthesis, the pathway that produces cholesterol and several non-sterol isoprenoids.
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PBA Preferentially Impairs Cell Survival of Glioblastomas Carrying mutp53 by Reducing Its Expression Level, Stabilizing wtp53, Downregulating the Mevalonate Kinase and Dysregulating UPR. [PDF]
Biomolecules, 2020 Romeo MA +5 more
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Correction: Directed evolution of mevalonate kinase in Escherichia coli by random mutagenesis for improved lycopene. [PDF]
RSC Adv, 2019 Chen H +5 more
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A case report of mevalonate kinase deficiency in a 14-month-old female with fevers and lower extremity weakness. [PDF]
BMC Pediatr, 2019 Coppola T +4 more
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HSCT in mevalonate kinase deficiency
Pediatric Rheumatology, 2013 Wolska-Kuśnierz, Beata +3 more
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Isoprenoid biosynthesis and mevalonate kinase deficiency
, 2011 Mevalonaat Kinase Deficiëntie (MKD) is een aangeboren ziekte geassocieerd met heftige koortsaanvallen die drie tot vier dagen aanhouden en gepaard gaan met koude rillingen, gewrichtsklachten, huiduitslag, hoofdpijn, duizeligheid, buikpijn, braken en diarree.
openaire +2 more sources
Mevalonate kinase deficiency presenting as recurrent rectal abscesses and perianal fistulae. [PDF]
Ann Allergy Asthma Immunol, 2018 Dunn K +5 more
europepmc +1 more source