Mevalonate kinase gene polymorphisms in ankylosing spondylitis patients: A cross-sectional study. [PDF]
Yıldız F, Dinkçi S, Erken E.
europepmc +1 more source
Characterization of a Feedback-Resistant Mevalonate Kinase from the Archaeon Methanosarcina mazei
The mevalonate pathway is utilized for the biosynthesis of isoprenoids in many bacterial, eukaryotic, and archaeal organisms. Based on previous reports of its feedback inhibition, mevalonate kinase (MVK) may play an important regulatory role in the ...
Mai Du +6 more
core +1 more source
The efficacy and safety of allogeneic stem cell transplantation in Mevalonate Kinase Deficiency. [PDF]
Jeyaratnam J +11 more
europepmc +1 more source
Mixed porokeratosis with a novel mevalonate kinase gene mutation: A case report. [PDF]
Xu HJ, Wen GD.
europepmc +1 more source
Summary: The induction of immunogenic cell death (ICD) impedes tumor progression via both tumor cell-intrinsic and -extrinsic mechanisms, representing a robust therapeutic strategy.
Liming Gui +5 more
doaj +1 more source
Inhibition of mevalonate kinase by disulfide compounds
Mevalonate kinase (I) of rat liver could use ADP in place of ATP at low, nonsaturated concentrations of mevalonate. I was inhibited when both dithiothreitol (DTT) and $Fe^{2+}$ (or $Fe^{3+})$ were added, and this inhibitory effect was obtained in Tris ...
Ramasarma, T, Lalitha, R, Kalpana, GV
core
Mechanistic insight into the role of mevalonate kinase by a natural fatty acid-mediated killing of Leishmania donovani. [PDF]
Prasad SR +15 more
europepmc +1 more source
We have previously reported a case of integration of HBV sequences in the 5′-noncoding region of the gene for mevalonate kinase (Mk) (EC.2.7.1.36) in the human hepatoma cell line PLC/PRF/5, resulting in overexpression of viral-cellular fusion transcripts
Koshy, R. +3 more
core +1 more source
An Atypical Presentation of Mevalonate Kinase Deficiency in Response to Colchicine Treatment. [PDF]
Koç Yekedüz M +5 more
europepmc +1 more source
Cutaneous manifestations in mevalonate kinase deficient patients treated with canakinumab
Canakinumab is a human monoclonal antibody anti-interleukin-1β, it is the only biologic drug approved to treat mevalonate kinase deficiency (MKD). Canakinumab injection can trigger several local cutaneous reactions, but also chronic-relapsing skin ...
Conte, Mariasole +4 more
core

