Results 191 to 200 of about 38,617 (240)

Pitavastatin induces autophagy-dependent ferroptosis in MDA-MB-231 cells via the mevalonate pathway. [PDF]

Heliyon
Tang WJ, Xu D, Liang MX, Wo GQ, Chen WQ, Tang JH, Zhang W.   +6 more
europepmc   +1 more source

The non-mevalonate pathway requires a delicate balance of intermediates to maximize terpene production. [PDF]

Appl Microbiol Biotechnol
Raghavan I, Juman R, Wang ZQ.
europepmc   +1 more source

Activation of the Mevalonate Pathway in Response to Anti-cancer Treatments Drives Glioblastoma Recurrences Through Activation of Rac-1. [PDF]

Cancer Res Commun
He L, Ioannidis A, Hoffman CJ, Arambula E, Joshi P, Whitelegge J, Liau LM, Kornblum HI, Pajonk F.   +8 more
europepmc   +1 more source

Two Novel and Three Recurrent Mutations in the Mevalonate Pathway Genes in Chinese Patients with Porokeratosis. [PDF]

Clin Cosmet Investig Dermatol
Wang X, Ouyang X, Zhang D, Zhu Y, Wu L, Xiao Z, Yu S, Li W, Li C.   +8 more
europepmc   +1 more source

Intramembrane protease SPP defines a cholesterol-regulated abundance control of the mevalonate pathway enzyme squalene synthase. [PDF]

J Biol Chem
Avci D, Heidasch R, Costa M, Lüchtenborg C, Kale D, Brügger B, Lemberg MK.   +6 more
europepmc   +1 more source

Correction to "Induction of Resistance to Neurotrophic Tropomyosin-Receptor Kinase Inhibitors by HMGCS2 via a Mevalonate Pathway". [PDF]

Cancer Med
europepmc   +1 more source

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Regulation of the mevalonate pathway

Nature, 1990
The mevalonate pathway produces isoprenoids that are vital for diverse cellular functions, ranging from cholesterol synthesis to growth control. Several mechanisms for feedback regulation of low-density-lipoprotein receptors and of two enzymes involved in mevalonate biosynthesis ensure the production of sufficient mevalonate for several end-products ...
J L, Goldstein, M S, Brown
openaire   +4 more sources

A mevalonate pathway–Hippo pathway connection

Nature Reviews Cancer, 2014
Gemma K Alderton
openaire   +3 more sources

Mevalonate pathway and male reproductive aging

Molecular Reproduction and Development, 2023
AbstractMale fertility declines with age. The mevalonate pathway, through which cholesterol and nonsteroidal isoprenoids are synthesized, plays key role in metabolic processes and is an essential pathway for cholesterol production and protein prenylation.
Jia‐Le Zhang, Meng Lv, Chao‐Fan Yang, Ying‐Xi Zhu, Chao‐Jun Li   +4 more
openaire   +2 more sources