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Metabolic control of YAP and TAZ by the mevalonate pathway
Nature Cell Biology, 2014The YAP and TAZ mediators of the Hippo pathway (hereafter called YAP/TAZ) promote tissue proliferation and organ growth. However, how their biological properties intersect with cellular metabolism remains unexplained. Here, we show that YAP/TAZ activity is controlled by the SREBP/mevalonate pathway.
Sorrentino G +12 more
openaire +4 more sources
The Mevalonate Pathway in Parasitic Protozoa and Helminths
Experimental Parasitology, 1996I, Coppens, P J, Courtoy
openaire +2 more sources
p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression
Cell, 2019Allison Mayle +2 more
exaly
Cholesterol and beyond - The role of the mevalonate pathway in cancer biology
Biochimica Et Biophysica Acta: Reviews on Cancer, 2020Tilman D Rachner +2 more
exaly
The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery
Cell, 2018Haitao Wu, Haiteng Deng, Eric Oldfield
exaly
Proceedings of the National Academy of Sciences of the United States of America, 2018
Hiroshi Kawaide +2 more
exaly
Hiroshi Kawaide +2 more
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