Results 171 to 180 of about 38,617 (240)

MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer. [PDF]

Cell Death Dis, 2023
Zheng YK, Zhou ZS, Wang GZ, Tu JY, Cheng HB, Ma SZ, Ke C, Wang Y, Jian QP, Shu YH, Wu XW.   +10 more
europepmc   +1 more source

Human γδ T Cell Function Is Impaired Upon Mevalonate Pathway Inhibition. [PDF]

Immunology
Suen TK, Al B, Ulas T, Reusch N, Bahrar H, Bekkering S, Bhat J, Kabelitz D, Schultze JL, van de Veerdonk FL, van Lennep JR, Riksen NP, Joosten LAB, Netea MG, Placek K.   +14 more
europepmc   +1 more source

Bone tumor-homing nanotherapeutics for prolonged retention in tumor microenvironment and facilitated apoptotic process via mevalonate pathway inhibition. [PDF]

Mater Today Bio, 2023
Kang NW, Visetvichaporn V, Nguyen DT, Shin EK, Kim D, Kim MJ, Yoo SY, Lee JY, Kim DD.   +8 more
europepmc   +1 more source

Mevalonate pathway-triggered phase transition of injectable hydrogel for cholesterol-downregulated therapy of osteoarthritis. [PDF]

Bioact Mater
Robby AI, Kim EH, Huh KM, Jin EJ, Park KD, Park SY.   +5 more
europepmc   +1 more source

A [4Fe-4S] cluster resides at the active center of phosphomevalonate dehydratase, a key enzyme in the archaeal modified mevalonate pathway. [PDF]

Front Microbiol, 2023
Komeyama M, Kanno K, Mino H, Yasuno Y, Shinada T, Ito T, Hemmi H.   +6 more
europepmc   +1 more source

Activity-based probes and chemical proteomics uncover the biological impact of targeting HMG-CoA Synthase 1 in the mevalonate pathway. [PDF]

J Biol Chem
Yi SA, Sun L, Rao Y, Ordureau A, Lewis JS, An H.   +5 more
europepmc   +1 more source

c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway. [PDF]

Biomedicines, 2022
Romeo MA, Gilardini Montani MS, Arena A, Benedetti R, D'Orazi G, Cirone M.   +5 more
europepmc   +1 more source

Regulation of glial ApoE secretion by the mevalonate pathway is independent of ApoE isoform. [PDF]

J Alzheimers Dis
Milstein JL, Kulas JA, Kamal A, Lo AB, Ferris HA.   +4 more
europepmc   +1 more source

MEMO: A Method for Computing Metabolic Modules for Cell-Free Production Systems

, 2020
Kamp von, A., Klamt, S.
core   +1 more source

An endothelial SOX18-mevalonate pathway axis enables repurposing of statins for infantile hemangioma. [PDF]

J Clin Invest
Holm A, Graus MS, Wylie-Sears J, Tan JWH, Alvarez-Harmon M, Borgelt L, Nasim S, Chung L, Jain A, Sun M, Sun L, Brouillard P, Lekwuttikarn R, Qi Y, Teng J, Vikkula M, Kozakewich H, Mulliken JB, Francois M, Bischoff J.   +19 more
europepmc   +1 more source