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Distribution of adjuvant MF59 and antigen gD2 after intramuscular injection in mice
Vaccine, 1999MF59, which is an adjuvant approved for human use, typically elicits higher antibody titers than alum when used in combination with a variety of recombinant and natural subunit antigens. The mechanisms responsible for the adjuvant action of MF59 are not fully understood.
M, Dupuis, D M, McDonald, G, Ott
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Mf59 ® -Adjuvanted Seasonalinfluenza Vaccine
Aging Health, 2009Correlated with increasing chronologic age, immunosenescence impairs the response to influenza vaccines. MF59®-adjuvanted influenza vaccine (Fluad®, Novartis, Basel, Switzerland) elicits a stronger and broader immune response against well-matched and drifted influenza strains compared with conventional vaccines. MF5-adjuvanted influenza vaccine reduces
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Vaccine, 1997
The immunogenicity and protective efficacy of influenza vaccine with and without the adjuvant MF59 was determined in mice. The addition of MF59 significantly increased the antibody response to the vaccine antigens over a wide dose range. Equivalent antibody titres were seen using 50- to 200-fold lower antigen concentrations when combined with MF59 ...
D M, Cataldo, G, Van Nest
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The immunogenicity and protective efficacy of influenza vaccine with and without the adjuvant MF59 was determined in mice. The addition of MF59 significantly increased the antibody response to the vaccine antigens over a wide dose range. Equivalent antibody titres were seen using 50- to 200-fold lower antigen concentrations when combined with MF59 ...
D M, Cataldo, G, Van Nest
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Journal of preventive medicine and hygiene, 2011
Journal of Preventive Medicine and Hygiene, Vol 52, No 1 (2011)
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Journal of Preventive Medicine and Hygiene, Vol 52, No 1 (2011)
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The adjuvanted influenza vaccines with novel adjuvants: experience with the MF59-adjuvanted vaccine
Vaccine, 2001Elderly people and subjects with underlying chronic diseases are at increased risk for influenza and related complications. Conventional influenza vaccines provide only limited protection in the elderly population. In order to enhance the immune response to influenza vaccines, several adjuvants have been evaluated. Among these, an oil in water adjuvant
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MF59-adjuvanted influenza vaccine cost effective
PharmacoEconomics & Outcomes News, 2020openaire +1 more source
Smart combination of aluminum hydroxide and MF59 to induce strong cellular immune responses
Journal of Controlled Release, 2022Xun Sun, Guangsheng Du, Yuanhao Zhao
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