Results 31 to 40 of about 7,531 (200)
Vaccines, 2022 Poloxamer-188 (P188) is a nonionic triblock linear copolymer that can be used as a pharmaceutical excipient because of its amphiphilic nature. This study investigated whether P188 can act as an adjuvant to improve the immunogenicity of severe acute ...
Chao-Hung Chen +4 more
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Innate immune responses in vivo after antigen administration : implications for vaccine development [PDF]
, 2015 Inducing high magnitude of antibodies with epitope breadth over prolonged periods of time is likely a prerequisite to prevent several of the world’s most serious infectious diseases such as HIV-1, malaria and tuberculosis for which there are no ...
Liang, Frank
core +1 more source
MF59™-adjuvanted seasonal influenza vaccine in young children
Expert Review of Vaccines, 2011 Influenza is a viral disease of the upper respiratory tract, which is manifested in seasonal epidemic waves associated with excess morbidity and mortality. Although efforts at prevention have traditionally been focused on the elderly, interest is growing on the specific features of influenza disease in children and the opportunities for prevention in ...
Puig-Barbera J +2 more
openaire +4 more sources
Human Vaccines & Immunotherapeutics, 2018 The poor immune response elicited by trivalent influenza vaccines (TIVs) in children can be enhanced by the addition of adjuvants. This observer-blind, randomized Phase III trial assessed the immunogenicity and safety of the MF59-adjuvanted trivalent ...
Aurelio Cruz-Valdez +7 more
doaj +1 more source
Safety of MF59-Adjuvanted Influenza Vaccination in the Elderly: Results of a Comparative Study of MF59-Adjuvanted Vaccine Versus Nonadjuvanted Influenza Vaccine in Northern Italy [PDF]
American Journal of Epidemiology, 2013 MF59-adjuvanted trivalent influenza vaccine (Novartis Vaccines and Diagnostics, Siena, Italy) has been shown to be more effective than nonadjuvanted vaccine in the elderly population. Here we present results from a large-scale, observational, noninterventional, prospective postlicensure study that evaluated the safety of MF59-adjuvanted vaccine in ...
VILLA, MARCO +15 more
openaire +3 more sources
Altered response to A(H1N1)pnd09 vaccination in pregnant women: a single blinded randomized controlled trial. [PDF]
PLoS ONE, 2013 Pregnant women were suspected to be at particular risk when H1N1pnd09 influenza became pandemic in 2009. Our primary objective was to compare the immune responses conferred by MF59®-adjuvanted vaccine (Focetria®) in H1N1pnd09-naïve pregnant and non ...
Anne Louise Bischoff +9 more
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Vaccines, 2021 Bovine viral diarrhea virus (BVDV) is a pathogen associated with substantial economic losses in the dairy cattle industry. Currently, there are no effective vaccines against BVDV.
Yi-Xuan Wang +4 more
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The post-2009 influenza pandemic era : time to revisit antibody immunodominance [PDF]
, 2018 The current inactivated influenza vaccines rely on the induction of neutralizing antibodies against the head domain of the viral hemagglutinin (HA). The HA head contains five immunodominant antigenic sites, all of which are subject to antigenic drift ...
Caton +6 more
core +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2020 The H1N1 influenza virus is known as a serious pandemic threat across the globe. Vaccination is one of the most effective methods of protection against this virus and the way to reduce the seasonal pandemic risk.
Niloufar Rashedi +4 more
doaj +1 more source
Development of MF-59 adjuvant using chitosan derivatives to influenza vaccine [PDF]
Journal of Advanced Biomedical Sciences, 2020 Background & Objective: The influenza virus causes hundreds of deaths in the world. Despite the availability of some authorized vaccines for all age groups and its approved beneficial effects, the influenza is still a major problem for public health ...
Alireza Loghmani +2 more
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