Results 71 to 80 of about 7,531 (200)

Deep phenotyping of the unselected COPSAC2010 birth cohort study [PDF]

, 2013
BACKGROUND: We hypothesize that perinatal exposures, in particular the human microbiome and maternal nutrition during pregnancy, interact with the genetic predisposition to cause an abnormal immune modulation in early life towards a trajectory to chronic
Bischoff, Anne Louise, Bisgaard, Hans Flinker, Bjarnadóttir, E., Bønnelykke, K., Carson, C. G., Chawes, Bo Lund Krogsgaard, Følsgaard, Nilofar Vahman, Kreiner‐Møller, E., Krogfelt, Karen Angeliki, Lauritzen, L., Mortensen, L. J., Nilsson, E., Olsen, S. F., Pedersen, L., Pedersen, Susanne Brix, Schjørring, S., Stokholm, J., Thysen, Anna Hammerich, Vissing, Nadja Hawwa   +18 more
core   +1 more source

Birth prevalence, clinical sequelae, and management of congenital cytomegalovirus infections in Australia, 1999–2023: a national prospective study

Medical Journal of Australia, Volume 223, Issue 11, Page 611-616, December 2025.
Abstract Objectives To investigate the birth prevalence, clinical manifestations, and management of congenital cytomegalovirus (CMV) infections in Australia, 1999–2023. Study design Longitudinal observational study; analysis of prospectively collected Australian Paediatric Surveillance Unit (APSU) data. Setting, participants Australia, 1 January 1999 –
Ece Egilmezer, Suzy M Teutsch, Carlos Nunez, Stuart T Hamilton, Adam W Bartlett, Pamela Palasanthiran, Elizabeth J Elliott, William D Rawlinson   +7 more
wiley   +1 more source

Fluad®-MF59®-Adjuvanted Influenza Vaccine in Older Adults

Infection & Chemotherapy, 2013
Influenza directly or indirectly contributes to the four leading causes of global mortality, at rates that are highest in older adults. As the proportion of older adults in the Korean population is greater than in most other countries, influenza prevention is a greater public health priority in Korea than elsewhere.
openaire   +2 more sources

The Immunogenicity of CpG, MF59-like, and Alum Adjuvant Delta Strain Inactivated SARS-CoV-2 Vaccines in Mice

Vaccines
The continuous evolution and mutation of SARS-CoV-2 have highlighted the need for more effective vaccines. In this study, CpG, MF59-like, and Alum adjuvant Delta strain inactivated SARS-CoV-2 vaccines were prepared, and the immunogenicity of these ...
Kangwei Xu, Jing Li, Xu Lu, Xiaoqin Ge, Kaiqin Wang, Jiahao Wang, Zhizhong Qiao, Yaru Quan, Changgui Li   +8 more
doaj   +1 more source

Alum adjuvant is more effective than MF59 at prompting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of a vaccine against opioid use disorders

Human Vaccines & Immunotherapeutics, 2019
Opioid use disorders (OUD) and fatal overdoses are a national emergency in the United States. Therapeutic vaccines offer a promising strategy to treat OUD and reduce the incidence of overdose.
Christine Robinson, Carly Baehr, Shirdi E. Schmiel, Claudia Accetturo, Daniel L. Mueller, Marco Pravetoni   +5 more
doaj   +1 more source

Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway

eLife, 2020
The squalene-based oil-in-water emulsion (SE) vaccine adjuvant MF59 has been administered to more than 100 million people in more than 30 countries, in both seasonal and pandemic influenza vaccines.
Eui Ho Kim, Matthew C Woodruff, Lilit Grigoryan, Barbara Maier, Song Hee Lee, Pratyusha Mandal, Mario Cortese, Muktha S Natrajan, Rajesh Ravindran, Huailiang Ma, Miriam Merad, Alexander D Gitlin, Edward S Mocarski, Joshy Jacob, Bali Pulendran   +14 more
doaj   +1 more source

Nanoparticle-Based Bivalent Swine Influenza Virus Vaccine Induces Enhanced Immunity and Effective Protection against Drifted H1N1 and H3N2 Viruses in Mice

Viruses, 2022
Swine influenza virus (SIV) circulates worldwide, posing substantial economic loss and disease burden to humans and animals. Vaccination remains the most effective way to prevent SIV infection and transmission.
Pan Tang, En-hui Cui, Wen-chi Chang, Chen Yu, Hao Wang, En-qi Du, Jing-yu Wang   +6 more
doaj   +1 more source

Impacto económico y sanitario de la utilización de vacuna antigripal adyuvada con MF59 en población mayor de 65 años en España [PDF]

, 2019
La gripe es un importante problema de salud, tanto por la mortalidad que puede provocar directa o indirectamente como por las complicaciones que ocasiona y los costes económicos y sociales que origina.
Rodríguez Márquez, Carlos, Rodríguez Pacheco, Jorge Ignacio   +1 more
core  

Influenza Virus Vaccine Efficacy Based On Conserved Sequence Alignment

, 2012
The rapid outbreak of bird flu challenges the outcome of effective vaccine for the upcoming years. The recent research established different norms to eliminate flu pandemics.
Jerald, Baby, Nair, T. R. Gopalakrishnan
core   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

Advanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez, Julio García‐Cordero, Gabriela Navarro‐Tovar, Leticia Cedillo‐Barrón   +3 more
wiley   +1 more source