Results 31 to 40 of about 909 (120)

Synthetic pro‐peptide design to enhance the secretion of heterologous proteins by Saccharomyces cerevisiae

open access: yesMicrobiologyOpen, Volume 11, Issue 3, June 2022., 2022
Saccharomyces cerevisiae is widely used for heterologous protein production but often secretes at comparatively low levels. To improve this, a secretion‐enhancing peptide cassette was added to the target protein and the pro‐peptide was optimized using three key parameters: N‐glycosylation, net negative charge balance, and glycine‐rich flexible linker ...
Ji Sung Cho   +7 more
wiley   +1 more source

Porphyromonas gingivalis fimbriae

open access: yesJournal of Oral Microbiology, 2013
Marginal periodontitis is not a homogeneous disease but is rather influenced by an intricate set of host susceptibility differences as well as diversities in virulence among the harbored organisms. It is likely that clonal heterogeneity of subpopulations
Morten Enersen   +2 more
doaj   +1 more source

Structural studies of the five pilin proteins building up the type-V pilus Mfa1 of Porphyromonas gingivalis [PDF]

open access: yesActa Crystallographica Section A Foundations and Advances, 2018
Structural studies of the five pilin proteins building up the type-V pilus Mfa1 of Porphyromonas ...
Karina Persson   +3 more
openaire   +1 more source

Mouse fetal antigen 1 (mFA1), the circulating gene product of mdlk, pref-1 and SCP-1: isolation, characterization and biology [PDF]

open access: yesReproduction, 1996
The mouse homologue to human fetal antigen 1 (hFA1) was purified from mouse amniotic fluid by cation exchange chromatography and immunospecific affinity chromatography. Mouse FA1 (mFA1) is a single chain glycoprotein with an M(r) of 42-50 kDa (SDS-PAGE). The N-terminal amino acid sequence (39 residues) revealed 74% identity to hFA1 and 100% identity to
Bachmann, E   +4 more
openaire   +3 more sources

Porphyromonas gingivalis Provokes Exosome Secretion and Paracrine Immune Senescence in Bystander Dendritic Cells

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Periodontitis is a disease of ageing or inflammaging, and is comorbid with other more severe age-related chronic diseases. With advanced age comes an increase in accumulation of senescent cells that release soluble and insoluble pro-inflammatory factors ...
Ranya Elsayed   +5 more
doaj   +1 more source

Disruption of Immune Homeostasis in Human Dendritic Cells via Regulation of Autophagy and Apoptosis by Porphyromonas gingivalis

open access: yesFrontiers in Immunology, 2019
As fundamental processes of immune homeostasis, autophagy, and apoptosis must be maintained to mitigate risk of chronic inflammation and autoimmune diseases.
Mohamed M. Meghil   +9 more
doaj   +1 more source

Oral community interactions of Filifactor alocis in vitro. [PDF]

open access: yesPLoS ONE, 2013
Filifactor alocis is a gram positive anaerobe that is emerging as an important periodontal pathogen. In the oral cavity F. alocis colonizes polymicrobial biofilm communities; however, little is known regarding the nature of the interactions between F ...
Qian Wang   +4 more
doaj   +1 more source

Tobacco upregulates P. gingivalis fimbrial proteins which induce TLR2 hyposensitivity.

open access: yesPLoS ONE, 2010
BackgroundTobacco smokers are more susceptible to periodontitis than non-smokers but exhibit reduced signs of clinical inflammation. The underlying mechanisms are unknown.
Juhi Bagaitkar   +5 more
doaj   +1 more source

Probiotics alter biofilm formation and the transcription of Porphyromonas gingivalis virulence-associated genes

open access: yesJournal of Oral Microbiology, 2020
Background and Objective The potential of probiotics on the prevention and control of periodontitis and other chronic inflammatory conditions has been suggested. Lactobacillus and Bifidobacterium species influence P.
Karin Hitomi Ishikawa   +6 more
doaj   +1 more source

Glycosylation Analysis and Protein Structure Determination of Murine Fetal Antigen 1 (mFA1) [PDF]

open access: yesEuropean Journal of Biochemistry, 1997
By means of sequence analysis, murine fetal antigen 1 (mFAl) isolated from Mus musculus amniotic fluid was shown to be the circulating protein of the δ‐like protein, stromal‐cell‐derived protein 1 (SCP‐1) and preadipocyte factor 1 (Pref‐1) gene products. The protein contains 36 cysteine residues arranged in six epidermal‐growth‐factor‐like domains. The
Krogh, T N   +4 more
openaire   +3 more sources

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