Results 21 to 30 of about 1,870 (159)

Role of Mfa5 in Expression of Mfa1 Fimbriae in Porphyromonas gingivalis [PDF]

Journal of Dental Research, 2016
Fimbriae are protein-based filamentous appendages that protrude from the bacterial cell surface and facilitate host adhesion. Two types of fimbriae, FimA and Mfa1, of the periodontal pathogen Porphyromonas gingivalis are responsible for adherence to other bacteria and to host cells in the oral cavity.
Y, Hasegawa, Y, Iijima, K, Persson, K, Nagano, Y, Yoshida, R J, Lamont, T, Kikuchi, A, Mitani, F, Yoshimura   +8 more
openaire   +3 more sources

Porphyromonas gingivalis Suppresses Interferon-Gamma Signaling in Macrophages Through a Contact-Dependent, Gingipain-Mediated Mechanism. [PDF]

Microbiologyopen
This study reveals that Porphyromonas gingivalis suppresses IFN‐γ signaling by downregulating STAT1 in macrophages. Gingipain protease activity and the Type IX Secretion System are essential for this immune evasion mechanism. These findings identify a novel bacterial strategy for host immune suppression and suggest new therapeutic targets for P ...
Abe S, Ohshima J, Morita M, Tanaka N, Hayashi M.   +4 more
europepmc   +2 more sources

Pathogenesis, Host Resistance and Integrated Management of Sugarcane Smut Caused by Sporisorium scitamineum: A Comprehensive Review. [PDF]

Mol Plant Pathol
This pathogen profile explores sugarcane (Saccharum spp.) smut caused by Sporisorium scitamineum, highlighting advances in pathogen biology, molecular pathogenesis, host resistance and management ABSTRACT Sugarcane smut, caused by the fungus Sporisorium scitamineum, is a devastating disease that threatens sugar production, leading to significant yield ...
Zeng Z, Wu Q, Wang D, Zhao W, Zhang Y, Sun T, Shen W, Que Y.   +7 more
europepmc   +2 more sources

Novel fimbrilin PGN_1808 in Porphyromonas gingivalis. [PDF]

PLoS ONE, 2017
Porphyromonas gingivalis, a periodontopathic gram-negative anaerobic bacterium, generally expresses two types of fimbriae, FimA and Mfa1. However, a novel potential fimbrilin, PGN_1808, in P.
Keiji Nagano, Yoshiaki Hasegawa, Yasuo Yoshida, Fuminobu Yoshimura   +3 more
doaj   +1 more source

Identification and Characterization of MFA1 , the Gene Encoding Candida albicans a -Factor Pheromone [PDF]

Eukaryotic Cell, 2007
ABSTRACT In the opaque state, MTL a and MTL α strains of Candida albicans are able to mate, and this mating is directed by a pheromone-mediated signaling process. We have used comparisons of genome sequences to identify a C. albicans
Dignard, Daniel, El-Naggar, Ahmed L., Logue, Mary E., Butler, Geraldine, Whiteway, Malcolm   +4 more
openaire   +2 more sources

Unraveling How Candida albicans Forms Sexual Biofilms. [PDF]

, 2020
Biofilms, structured and densely packed communities of microbial cells attached to surfaces, are considered to be the natural growth state for a vast majority of microorganisms.
Hernday, Aaron D, Nobile, Clarissa J, Perry, Austin M   +2 more
core   +1 more source

Anchoring and length regulation of Porphyromonas gingivalis Mfa1 fimbriae by the downstream gene product Mfa2 [PDF]

Microbiology, 2009
Porphyromonas gingivalis, a causative agent of periodontitis, has at least two types of thin, single-stranded fimbriae, termed FimA and Mfa1 (according to the names of major subunits), which can be discriminated by filament length and by the size of their major fimbrilin subunits.
Yoshiaki, Hasegawa, Jun, Iwami, Keiko, Sato, Yoonsuk, Park, Kiyoshi, Nishikawa, Tatsuo, Atsumi, Keiichi, Moriguchi, Yukitaka, Murakami, Richard J, Lamont, Hiroshi, Nakamura, Norikazu, Ohno, Fuminobu, Yoshimura   +11 more
openaire   +2 more sources

Phylogenetic diversity in fim and mfa gene clusters between Porphyromonas gingivalis and Porphyromonas gulae, as a potential cause of host specificity

Journal of Oral Microbiology, 2020
Background Periodontopathic bacteria Porphyromonas gingivalis in humans and Porphyromonas gulae in animals are phylogenetically close and commonly have FimA and Mfa1 fimbriae.
Kaori Fujiwara-Takahashi, Takayasu Watanabe, Masahiro Shimogishi, Masaki Shibasaki, Makoto Umeda, Yuichi Izumi, Ichiro Nakagawa   +6 more
doaj   +1 more source

A Multiplex GPCR‐Mediated Peptide Tagging System for a Growing Yeast Synthetic Biology Toolbox

Helvetica Chimica Acta, Volume 106, Issue 12, December 2023., 2023
Abstract Straightforward methods for specifically detecting and quantifying proteins are essential for both basic and applied research and notably in synthetic biology. Previously we demonstrated that the yeast mating pathway could be hijacked to detect species‐specific fungal peptide pheromones using their corresponding mating GPCRs.
Joseph Matragrano, Virginia W. Cornish, Sonja Billerbeck   +2 more
wiley   +1 more source

Draft Genome Sequence of Porphyromonas gingivalis Strain Ando Expressing a 53-Kilodalton-Type Fimbrilin Variant of Mfa1 Fimbriae [PDF]

Genome Announcements, 2015
ABSTRACT Periodontopathic Porphyromonas gingivalis strain Ando abundantly expresses a 53-kDa-type Mfa1 fimbria. Here, we report the draft genome sequence of Ando, with a size of 2,229,994 bp, average G+C content of 48.4%, and 1,755 predicted protein-coding sequences.
Goto, Takatsugu, Nagano, Keiji, Hirakawa, Hideki, Tanaka, Kaori, Yoshimura, Fuminobu   +4 more
openaire   +2 more sources