Herbal Composite Preparation and Investigating its Efficiency to Inhibit Biofilm Formation and Virulence Factors of Prevotella Intermedia and Porphyromonas Gingivalis – Formulation of Mouthwash Using a Herbal Composite and Evaluating its Anti-microbial Activity [PDF]
Journal of Pharmacy and Bioallied SciencesHerbal composite preparation was studied with the aim of inhibiting the virulence factors of two dental pathogens: Prevotella intermedia and Porphyromonas gingivalis.
Murugan Manohar +5 more
doaj +2 more sources
Proteomics of Periodontitis-Associated Bacteria and Its Link to Oral Squamous Cell Carcinoma: A Contemporaneous Review [PDF]
International Dental Journal: Introduction and aims: Periodontitis, a chronic inflammatory disease of the periodontium, causes gingival inflammation and bone loss. Meanwhile, oral cancer synonymously known as oral squamous cell carcinoma is characterised by uncontrolled cell ...
ShueKang Yeong +3 more
doaj +2 more sources
An Oxygen-Releasing Mouthwash Reduces Porphyromonas gingivalis Biofilm and Suppresses fimA and hagA Expression [PDF]
International Dental JournalIntroduction and Aims: Porphyromonas gingivalis is a key periodontal pathogen whose biofilm and virulence limit the effectiveness of mouthwashes such as chlorhexidine (CHX).
Fatemah M. AlAhmari +8 more
doaj +2 more sources
Identification of the mechanism for dehalorespiration of monofluoroacetate in the phylum Synergistota [PDF]
Animal BioscienceObjective Monofluoroacetate (MFA) is a potent toxin that blocks ATP production via the Krebs cycle and causes acute toxicity in ruminants consuming MFA-containing plants.
Lex E. X. Leong +5 more
doaj +2 more sources
Structural and functional characterization of shaft, anchor, and tip proteins of the Mfa1 fimbria from the periodontal pathogen Porphyromonas gingivalis [PDF]
Scientific Reports, 2018 AbstractVery little is known about how fimbriae of Bacteroidetes bacteria are assembled. To shed more light on this process, we solved the crystal structures of the shaft protein Mfa1, the regulatory protein Mfa2, and the tip protein Mfa3 from the periodontal pathogen Porphyromonas gingivalis.
Fuminobu Yoshimura +2 more
exaly +5 more sources
Antibacterial Activity, Antiadherence Activity, Antioxidant Activity, and Molecular Docking of Sweetbrair Rose (Rosa Rubiginosa) Extract on Periodontopathogens: Porphyromonas Gingivalis and Aggregatibacter Actinomycetemcomitans – An In Vitro Study [PDF]
Journal of Pharmacy and Bioallied SciencesIntroduction: Rosa rubiginosa extracts were prepared, and the antibacterial and anti-biofilm assays were investigated against two different periodontics-causing bacteria for the first time. The aim was to determine whether the extracts could restrict the
Syed Wali Peeran +7 more
doaj +2 more sources
Phylogenomic analysis of the Porphyromonas gingivalis - Porphyromonas gulae duo: approaches to the origin of periodontitis [PDF]
Frontiers in Microbiology, 2023 Porphyromonas gingivalis is an oral human pathogen associated with the onset and progression of periodontitis, a chronic immune-inflammatory disease characterized by the destruction of the teeth-supporting tissue. P.
Mauricio Morales-Olavarría +8 more
doaj +2 more sources
Porphyromonas gingivalis Suppresses Interferon-Gamma Signaling in Macrophages Through a Contact-Dependent, Gingipain-Mediated Mechanism. [PDF]
MicrobiologyopenThis study reveals that Porphyromonas gingivalis suppresses IFN‐γ signaling by downregulating STAT1 in macrophages. Gingipain protease activity and the Type IX Secretion System are essential for this immune evasion mechanism. These findings identify a novel bacterial strategy for host immune suppression and suggest new therapeutic targets for P ...
Abe S +4 more
europepmc +2 more sources
Draft Genome Sequence of Porphyromonas gingivalis Strain Ando Expressing a 53-Kilodalton-Type Fimbrilin Variant of Mfa1 Fimbriae [PDF]
Genome Announcements, 2015 ABSTRACT Periodontopathic Porphyromonas gingivalis strain Ando abundantly expresses a 53-kDa-type Mfa1 fimbria. Here, we report the draft genome sequence of Ando, with a size of 2,229,994 bp, average G+C content of 48.4%, and 1,755 predicted protein-coding sequences.
Fuminobu Yoshimura, Keiji Nagano
exaly +3 more sources
Giant honeybees (Apis dorsata) trade off defensiveness against periodic mass flight activity. [PDF]
PLoS ONEThe giant honeybee Apis dorsata (Fabricius, 1793) is an evolutionarily ancient species that builds its nests in the open. The nest consists of a single honeycomb covered with the bee curtain which are several layers of worker bees that remain almost ...
Gerald Kastberger +2 more
doaj +2 more sources