Results 121 to 130 of about 39,147 (253)
Building nonparametric $n$-body force fields using Gaussian process regression
Constructing a classical potential suited to simulate a given atomic system is a remarkably difficult task. This chapter presents a framework under which this problem can be tackled, based on the Bayesian construction of nonparametric force fields of a ...
A Glielmo +58 more
core +1 more source
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li +5 more
wiley +1 more source
A Neglected Aspect of the Debates on the EU Budget: Duration of the MFF [PDF]
In May 2018, the European Commission published its proposal on the Multiannual Financial Framework (MFF) for the period 2021–2027. Preparation for the post-2020 MFF requires comprehensive analysis of the characteristic features of the EU budget and of the priorities that should be supported at the EU level.
openaire +2 more sources
Melatonin restores testosterone production in aging Leydig cells by targeting key pathological drivers, particularly oxidative stress and mitochondrial dysfunction. This approach offers a fundamental strategy to reshape the Late‐onset hypogonadism treatment paradigm.
Hui Wu +6 more
wiley +1 more source
Effect of Low-Frequency Magnetic Field Assisted Freezing Time on Physicochemical Properties, Moisture Migration and Rheological Properties of Pork [PDF]
This study was conducted to evaluate the effect of low-frequency alternating magnetic field assisted freezing (LF-MFF, –18 ℃) for different periods (12, 24, 36 and 48 h) on the quality of pork using fresh meat and conventional refrigerator freezing (–18 ℃
LI Huijie, ZONG Jiaxing, HU Yanyan, ZHAO Shengming, WANG Hui, ZHU Mingming, MA Hanjun
doaj +1 more source
FAM162A, localized within mitochondrial cristae, emerges as a novel regulator of mitochondrial dynamics. It post‐translationally modulates OPA1, maintaining cristae structure and boosting cellular bioenergetics. This key interaction enhances cell viability, stress resistance, and overall organismal health.
Andrea Matamoros +11 more
wiley +1 more source
Scalar Meson Spectroscopy with Lattice Staggered Fermions
With sufficiently light up and down quarks the isovector ($a_0$) and isosinglet ($f_0$) scalar meson propagators are dominated at large distance by two-meson states.
C. Bernard +9 more
core +1 more source
Mechanical Force Promotes Mitochondrial Transfer From Macrophages to BMSCs to Enhance Bone Formation
Mechanical tension activates Drp1‐mediated mitochondrial fission in macrophages, facilitating the release of Mito‐EVs that are subsequently transferred to BMSCs. Additionally, the CD200R‐CD200 interaction enhances the uptake of these mechanically stimulated macrophage‐derived Mito‐EVs by BMSCs, ultimately promoting osteogenic differentiation.
Yingyi Li +8 more
wiley +1 more source
A modified formula for calculating low-density lipoprotein cholesterol values
Background The Friedewald formula (FF) is useful for calculating serum low-density lipoprotein cholesterol (LDL-C) values, but has a remarkable deviation and limitation especially in hypertriglyceridemia.
Chen Bin +8 more
doaj +1 more source

