454 screening of individual MHC variation in an endemic island passerine [PDF]
Genes of the major histocompatibility complex (MHC) code for receptors that are central to the adaptive immune response of vertebrates. These genes are therefore important genetic markers with which to study adaptive genetic variation in the wild.
Gonzalez Quevedo, Catalina +3 more
core +2 more sources
Improved haplotype resolution of highly duplicated MHC genes in a long-read genome assembly using MiSeq amplicons [PDF]
Long-read sequencing offers a great improvement in the assembly of complex genomic regions, such as the major histocompatibility complex (MHC) region, which can contain both tandemly duplicated MHC genes (paralogs) and high repeat content.
Samantha Mellinger +4 more
doaj +2 more sources
Modular Nucleic Acid Assembled p/MHC Microarrays for Multiplexed Sorting of Antigen-Specific T Cells [PDF]
The human immune system consists of a large number of T cells capable of recognizing and responding to antigens derived from various sources. The development of peptide-major histocompatibility (p/MHC) tetrameric complexes has enabled the direct ...
Bailey, Ryan C. +12 more
core +2 more sources
Objectives: Pathological gambling (PG) is a highly prevalent and disabling impulse control disorder. A range of psychopharmacological options are available for the treatment of PG, including selective serotonin reuptake inhibitors (SSRI), opioid receptor
Pinhas N Dannon, Pinhas N Dannon
doaj +1 more source
Redistribution of critical major histocompatibility complex and T cell receptor-binding functions of residues in an antigenic sequence after biterminal substitution [PDF]
Residues critical for establishing a trimolecular interaction with a major histocompatibility complex (MHC)-encoded receptor and a T cell antigen receptor (TcR) were determined for an antigenic nonapeptide. The N-terminal residue proved to be involved in
Allen +18 more
core +1 more source
Morphometric analysis of the posed smile A comparison between normal occlusion, class 1 malocclusion and non-extraction treated group [PDF]
Aim: Lips-Dentition relationships play a special role during smile. Present study compared the relationship of lips and teeth during posed smile in subjects with normal occlusion, class 1 malocclusion and non-extraction treated cases.
Amirfarhang Miresmaeili +3 more
doaj +1 more source
Contrasting patterns of selection between MHC I and II across populations of Humboldt and Magellanic penguins [PDF]
Indexación: Web of ScienceThe evolutionary and adaptive potential of populations or species facing an emerging infectious disease depends on their genetic diversity in genes, such as the major histocompatibility complex (MHC). In birds, MHC class I deals
Dantas, GPM +7 more
core +1 more source
Expression of CD226 is associated to but not required for NK cell education [PDF]
DNAX accessory molecule-1 (DNAM-1, also known as CD226) is an activating receptor expressed on subsets of natural killer (NK) and T cells, interacts with its ligands CD155 or CD112, and has co-varied expression with inhibitory receptors. Since inhibitory
Bernhardt, Günter +9 more
core +2 more sources
Background: Adaptation is an accepted part of implementing evidence-based practices. COVID-19 presented a unique opportunity to examine adaptation in evolving contexts.
Holly A. Hills +5 more
doaj +1 more source
Forecast of cytotoxic T lymphocyte epitope using sequence weighting and artificial neural network based on EasyPred modeler [PDF]
Aim: Cytotoxic T lymphocytes (CTL) examine the major histocompatibility complex (MHC) class I ligands on nucleated cells to detect antigens derived from pathogens and cancer cells.
Satarudra Prakash Singh +2 more
doaj +1 more source

