Results 21 to 30 of about 317,787 (293)

Morphometric analysis of the posed smile A comparison between normal occlusion, class 1 malocclusion and non-extraction treated group [PDF]

open access: yesIranian Journal of Orthodontics, 2006
Aim: Lips-Dentition relationships play a special role during smile. Present study compared the relationship of lips and teeth during posed smile in subjects with normal occlusion, class 1 malocclusion and non-extraction treated cases.
Amirfarhang Miresmaeili   +3 more
doaj   +1 more source

MHC I stabilizing potential of computer-designed octapeptides [PDF]

open access: yes, 2010
Experimental results are presented for 180 in silico designed octapeptide sequences and their stabilizing effects on the major histocompatibility class I molecule H-2Kb.
Jäger, Natalie   +20 more
core   +1 more source

Rapid adaptation during the COVID crisis: Challenges experienced in delivering service to those with Opioid Use Disorders

open access: yesImplementation Research and Practice, 2022
Background: Adaptation is an accepted part of implementing evidence-based practices. COVID-19 presented a unique opportunity to examine adaptation in evolving contexts.
Holly A. Hills   +5 more
doaj   +1 more source

Reconstructing Macroevolutionary Patterns in Avian MHC Architecture With Genomic Data

open access: yesFrontiers in Genetics, 2022
The Major Histocompatibility Complex (MHC) is a hyper-polymorphic genomic region, which forms a part of the vertebrate adaptive immune system and is crucial for intra- and extra-cellular pathogen recognition (MHC-I and MHC-IIA/B, respectively).
Ke He   +5 more
doaj   +1 more source

Improved haplotype resolution of highly duplicated MHC genes in a long-read genome assembly using MiSeq amplicons [PDF]

open access: yesPeerJ, 2023
Long-read sequencing offers a great improvement in the assembly of complex genomic regions, such as the major histocompatibility complex (MHC) region, which can contain both tandemly duplicated MHC genes (paralogs) and high repeat content.
Samantha Mellinger   +4 more
doaj   +2 more sources

Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history [PDF]

open access: yes, 2006
The major histocompatibility complex (MHC) is recognised as one of the most important genetic regions in relation to common human disease. Advancement in identification of MHC genes that confer susceptibility to disease requires greater knowledge of ...
John Trowsdale   +64 more
core   +1 more source

Forecast of cytotoxic T lymphocyte epitope using sequence weighting and artificial neural network based on EasyPred modeler [PDF]

open access: yesExploration of Immunology
Aim: Cytotoxic T lymphocytes (CTL) examine the major histocompatibility complex (MHC) class I ligands on nucleated cells to detect antigens derived from pathogens and cancer cells.
Satarudra Prakash Singh   +2 more
doaj   +1 more source

Expression of MHC Class I and II in Growing Ovarian Follicles of Young and Old Laying Hens, Gallus domesticus

open access: yesThe Journal of Poultry Science, 2005
The aim of this study was to determine whether the expressions of MHC class I and II in the ovarian follicles change with follicular growth and aging of birds. Theca layer of white follicles (WF), the largest and the third largest preovulatory follicles
Kalpana Subedi, Yukinori Yoshimura
doaj   +1 more source

High functional allelic diversity and copy number in both MHC classes in the common buzzard

open access: yesBMC Ecology and Evolution, 2023
Background The major histocompatibility complex (MHC), which encodes molecules that recognize various pathogens and parasites and initiates the adaptive immune response in vertebrates, is renowned for its exceptional polymorphism and is a model of ...
Jamie Winternitz   +4 more
doaj   +1 more source

EXPRESSION OF A FUNCTIONAL CHIMERIC lg-MHC CLASS II PROTEIN [PDF]

open access: yes, 1992
composed of the a- and ß-chains of the MHC class I1 I-E molecule fused to antibody V regions derived from anti-human CD4 mAb MT310. Expression vectors were constructed containing the functional, rearranged gene segments coding for the V region domains of
Zwirner, Jörg   +8 more
core   +1 more source

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