Results 21 to 30 of about 290,788 (308)

Rapid adaptation during the COVID crisis: Challenges experienced in delivering service to those with Opioid Use Disorders

open access: yesImplementation Research and Practice, 2022
Background: Adaptation is an accepted part of implementing evidence-based practices. COVID-19 presented a unique opportunity to examine adaptation in evolving contexts.
Holly A. Hills   +5 more
doaj   +1 more source

Reconstructing Macroevolutionary Patterns in Avian MHC Architecture With Genomic Data

open access: yesFrontiers in Genetics, 2022
The Major Histocompatibility Complex (MHC) is a hyper-polymorphic genomic region, which forms a part of the vertebrate adaptive immune system and is crucial for intra- and extra-cellular pathogen recognition (MHC-I and MHC-IIA/B, respectively).
Ke He   +5 more
doaj   +1 more source

Forecast of cytotoxic T lymphocyte epitope using sequence weighting and artificial neural network based on EasyPred modeler [PDF]

open access: yesExploration of Immunology
Aim: Cytotoxic T lymphocytes (CTL) examine the major histocompatibility complex (MHC) class I ligands on nucleated cells to detect antigens derived from pathogens and cancer cells.
Satarudra Prakash Singh   +2 more
doaj   +1 more source

Expression of MHC Class I and II in Growing Ovarian Follicles of Young and Old Laying Hens, Gallus domesticus

open access: yesThe Journal of Poultry Science, 2005
The aim of this study was to determine whether the expressions of MHC class I and II in the ovarian follicles change with follicular growth and aging of birds. Theca layer of white follicles (WF), the largest and the third largest preovulatory follicles
Kalpana Subedi, Yukinori Yoshimura
doaj   +1 more source

High functional allelic diversity and copy number in both MHC classes in the common buzzard

open access: yesBMC Ecology and Evolution, 2023
Background The major histocompatibility complex (MHC), which encodes molecules that recognize various pathogens and parasites and initiates the adaptive immune response in vertebrates, is renowned for its exceptional polymorphism and is a model of ...
Jamie Winternitz   +4 more
doaj   +1 more source

Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours

open access: yesOpen Biology, 2022
MHC-I and MHC-II molecules are critical components of antigen presentation and T cell immunity to pathogens and cancer. The two monoclonal transmissible devil facial tumours (DFT1, DFT2) exploit MHC-I pathways to overcome immunological anti-tumour and ...
Chrissie E. B. Ong   +5 more
doaj   +1 more source

Gene duplication and fragmentation in the zebra finch major histocompatibility complex [PDF]

open access: yes, 2010
BACKGROUND: Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects.
Tina Graves   +54 more
core   +1 more source

MHC-II binding prediction results of VirB8 (IEDB).

open access: yes, 2023
MHC-II binding prediction results of VirB8 (IEDB).
Ce Niu (16814125)   +10 more
core   +1 more source

MHC-II binding prediction results of VirB10 (IEDB).

open access: yes, 2023
MHC-II binding prediction results of VirB10 (IEDB).
Ce Niu (16814125)   +10 more
core   +1 more source

Patterns of MHC-G-Like and MHC-B Diversification in New World Monkeys. [PDF]

open access: yesPLoS ONE, 2015
The MHC class I (MHC-I) region in New World monkeys (Platyrrhini) has remained relatively understudied. To evaluate the diversification patterns and transcription behavior of MHC-I in Platyrrhini, we first analyzed public genomic sequences from the MHC-G-
Juan S Lugo, Luis F Cadavid
doaj   +1 more source

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