MHC-linked and un-linked class I genes in the wallaby [PDF]
, 2009 Background: MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune functions.
Wong, Emily S. W. +39 more
core +1 more source
DISTRIBUTION OF MICA ALLELES IN THE RUSSIAN POPULATION
Медицинская иммунология, 2019 Stress factors, infections, tumor transformation of the cells of organism induce the expression of MICA protein, which is a ligand for the NKG2D receptor of NK and T cells.
L. M. Kanevskiy +6 more
doaj +1 more source
Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules [PDF]
, 1997 Major histocompatibility complex (MHC) class II molecules are transported to intracellular MHC class II compartments via a transient association with the invariant chain (Ii).
Pieters, J. +11 more
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Statistical deconvolution of enthalpic energetic contributions to MHC-peptide binding affinity [PDF]
, 2006 Background: MHC Class I molecules present antigenic peptides to cytotoxic T cells, which forms an integral part of the adaptive immune response. Peptides are bound within a groove formed by the MHC heavy chain. Previous approaches to MHC Class I-peptide
Hattotuwagama, C.K. +18 more
core +1 more source
Improved haplotype resolution of highly duplicated MHC genes in a long-read genome assembly using MiSeq amplicons [PDF]
PeerJ, 2023 Long-read sequencing offers a great improvement in the assembly of complex genomic regions, such as the major histocompatibility complex (MHC) region, which can contain both tandemly duplicated MHC genes (paralogs) and high repeat content.
Samantha Mellinger +4 more
doaj +2 more sources
MHC I stabilizing potential of computer-designed octapeptides [PDF]
, 2010 Experimental results are presented for 180 in silico designed octapeptide sequences and their stabilizing effects on the major histocompatibility class I molecule H-2Kb.
Jäger, Natalie +20 more
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Frontiers in Psychiatry, 2011 Objectives: Pathological gambling (PG) is a highly prevalent and disabling impulse control disorder. A range of psychopharmacological options are available for the treatment of PG, including selective serotonin reuptake inhibitors (SSRI), opioid receptor
Pinhas N Dannon, Pinhas N Dannon
doaj +1 more source
Morphometric analysis of the posed smile A comparison between normal occlusion, class 1 malocclusion and non-extraction treated group [PDF]
Iranian Journal of Orthodontics, 2006 Aim: Lips-Dentition relationships play a special role during smile. Present study compared the relationship of lips and teeth during posed smile in subjects with normal occlusion, class 1 malocclusion and non-extraction treated cases.
Amirfarhang Miresmaeili +3 more
doaj +1 more source
Down-regulation of MHC class I is a property common to papillomavirus E5 proteins [PDF]
, 2006 The E5 protein family of papillomaviruses comprises small hydrophobic proteins which are associated with the cell endomembrane compartments. The functions of the E5 proteins, particularly those of HPV, are still far from clear.
Fife, K.H. +11 more
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EXPRESSION OF A FUNCTIONAL CHIMERIC lg-MHC CLASS II PROTEIN [PDF]
, 1992 composed of the a- and ß-chains of the MHC class I1 I-E molecule fused to antibody V regions derived from anti-human CD4 mAb MT310. Expression vectors were constructed containing the functional, rearranged gene segments coding for the V region domains of
Zwirner, Jörg +8 more
core +1 more source