Open Biology, 2022 MHC-I and MHC-II molecules are critical components of antigen presentation and T cell immunity to pathogens and cancer. The two monoclonal transmissible devil facial tumours (DFT1, DFT2) exploit MHC-I pathways to overcome immunological anti-tumour and ...
Chrissie E. B. Ong +5 more
doaj +1 more source
Cryptic female choice favours sperm from major histocompatibility complex-dissimilar males [PDF]
, 2013 Cryptic female choice may enable polyandrous females to avoid inbreeding or bias offspring variability at key loci after mating. However, the role of these genetic benefits in cryptic female choice remains poorly understood. Female red junglefowl, Gallus
Alcaide M +8 more
core +1 more source
Gapped sequence alignment using artificial neural networks: application to the MHC class I system
Bioinform., 2016 MOTIVATION Many biological processes are guided by receptor interactions with linear ligands of variable length. One such receptor is the MHC class I molecule. The length preferences vary depending on the MHC allele, but are generally limited to peptides
M. Andreatta, M. Nielsen
semanticscholar +1 more source
High functional allelic diversity and copy number in both MHC classes in the common buzzard
BMC Ecology and Evolution, 2023 Background The major histocompatibility complex (MHC), which encodes molecules that recognize various pathogens and parasites and initiates the adaptive immune response in vertebrates, is renowned for its exceptional polymorphism and is a model of ...
Jamie Winternitz +4 more
doaj +1 more source
Major Histocompatibility Complex I and II Expression and Lymphocytic Subtypes in Muscle of Horses with Immune-Mediated Myositis. [PDF]
, 2016 BackgroundMajor histocompatibility complex (MHC) I and II expression is not normally detected on sarcolemma, but is detected with lymphocytic infiltrates in immune-mediated myositis (IMM) of humans and dogs and in dysferlin-deficient muscular dystrophy ...
Barnes, N +6 more
core +1 more source
Science Translational Medicine, 2018 Loss of membrane MHC class I protein expression in most of tumor cells in advanced melanomas predicts primary resistance to anti–CTLA-4, but not anti-PD1, treatment.
S. Rodig +17 more
semanticscholar +1 more source
Patterns of MHC-G-Like and MHC-B Diversification in New World Monkeys. [PDF]
PLoS ONE, 2015 The MHC class I (MHC-I) region in New World monkeys (Platyrrhini) has remained relatively understudied. To evaluate the diversification patterns and transcription behavior of MHC-I in Platyrrhini, we first analyzed public genomic sequences from the MHC-G-
Juan S Lugo, Luis F Cadavid
doaj +1 more source
Kinetics of lithium electrodeposition and stripping [PDF]
J. Chem. Phys. 153, 194701 (2020), 2020 Electrodeposition and stripping are fundamental electrochemical processes for metals and have gained importance in rechargeable Li-ion batteries due to lithium metal electrodes. The electrode kinetics associated with lithium metal electrodeposition and stripping is crucial in determining performance at fast discharge and charge which is important for ...
arxiv +1 more source
INITIAL CHARACTERIZATION OF MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) CLASS IIB EXON 2 IN AN ENDANGERED RATTLESNAKE, THE EASTERN MASSASAUGA (SISTRURUS CATENATUS) [PDF]
, 2014 Genes of the major histocompatibility complex (MHC) play an important role in the vertebrate immune system and exhibit remarkably high levels of polymorphism, maintained by strong balancing selection.
Duvall, Melvin R. +2 more
core +2 more sources
March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity. [PDF]
, 2018 In transplantation, donor dendritic cells (do-DCs) initiate the alloimmune response either by direct interaction with host T cells or by transferring intact donor MHC to host DCs.
Abdi, Reza +21 more
core +3 more sources