Results 91 to 100 of about 255,748 (249)

CIITA-induced occupation of MHC class II promoters is independent of the cooperative stabilization of the promoter-bound multi-protein complexes [PDF]

, 2017
Precise regulation of MHC class II expression plays a crucial role in the control of the immune response. The transactivator CIITA behaves as a master controller of constitutive and inducible MHC class II gene activation, but its exact mechanism of ...
Bontron, Séverine, Mach, Bernard, Muhlethaler-Mottet, Annick, Reith, Walter, Villard, Jean   +4 more
core  

Antigen loading of MHC class I molecules in the endocytic tract [PDF]

, 2001
Major histocompatibility complex (MHC) class I molecules bind antigenic peptides that are translocated from the cytosol into the endoplasmic reticulum by the transporter associated with antigen processing.
Albert, Amigorena, Aragnol, Arnold-Schild, Bachmann, Banchereau, Barnstable, Bevan, Campbell, Castellino, Cresswell, Dasgupta, De Bruijn, Escola, Germain, Geuze, Griffin, Grommé, Hammond, Harding, Huang, Johnstone, Jondal, Keene, Kleijmeer, Kleijmeer, Kovacsovics-Bankowski, Lamb, Liu, Liu, Matzinger, Mellins, Morton, Neuman, Norbury, Pan, Peters, Pfeifer, Raposo, Raposo, Reid, Reis e Sousa, Ridge, Rock, Rock, Rodriguez, Romani, Schirmbeck, Schirmbeck, Schirmbeck, Schoenberger, Spies, Sugita, Théry, Townsend, Trowsdale, Tse, Ulmer, Urban, Van Binnendijk, Vega, Vigna, Watts, West, Wolf, Yewdell, Zhou, Ziegler, Zitvogel   +68 more
core   +2 more sources

Endogenous antigen presentation of MHC class II epitopes through non-autophagic pathways

Frontiers in Immunology, 2015
Antigenic peptides presented by major histocompatibility complex (MHC) class II molecules are generally derived from exogenous proteins acquired by antigen presenting cells. However, in some circumstances, MHC class II molecules can present intracellular
Carol Sze Ki eLeung
doaj   +1 more source

Mouse CD4 binds MHC class II with extremely low affinity [PDF]

, 2017
Interaction of CD4 with MHC class II molecules plays a crucial role during thymic development and activation of singie-positive CD4 T lymphocytes. The quantitation of this interaction is, therefore, important for understanding the role of CD4 during ...
Karjalainen, Klaus, Weber, Susanna
core  

Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan [PDF]

, 2008
CD4 positive T helper cells control many aspects of specific immunity. These cells are specific for peptides derived from protein antigens and presented by molecules of the extremely polymorphic major histocompatibility complex (MHC) class II system. The
A Haque, A Sette, A Sette, A Sette, Alessandro Sette, B Boeckmann, B Peters, Bjoern Peters, C Lundegaard, C Sylvester-Hvid, Claus Lundegaard, D Middleton, F Castellino, H Noguchi, H Rammensee, H Singh, HH Bui, HM Berman, IA Doytchinova, J Alexander, J Cui, J Robinson, J Salomon, J Wan, JA Swets, JK Christensen, JW Yewdell, L Gauthier, M Moutaftsi, M Nielsen, M Nielsen, M Nielsen, M Nielsen, M Rajapakse, Morten Nielsen, N Murugan, O Karpenko, O Lund, Ole Lund, Ruth Nussinov, S Henikoff, SL Lauemoller, ST Chang, Sune Justesen, Søren Buus, T Sturniolo, Thomas Blicher, U Hobohm, V Brusic, WH Press   +49 more
core   +4 more sources

Supplementary Table 1 from MHC Class II is Induced by IFNγ and Follows Three Distinct Patterns of Expression in Colorectal Cancer Organoids

, 2023
Oliver Pickles, Kasun Wanigasooriya, Anetta Ptasinska, Akshay J. Patel, Helen L. Robbins, Claire Bryer, Celina Whalley, Louise Tee, Neeraj Lal, Claudia M.A. Pinna, Nahla Elzefzafy, Philippe Tanière, Andrew D. Beggs, Gary Middleton   +13 more
openalex   +2 more sources

Of LAP, CUPS and DRibbles – unconventional use of autophagy proteins for MHC restricted antigen presentation

Frontiers in Immunology, 2015
Macroautophagy delivers cytoplasmic constituents for lysosomal degradation. Since MHC class II molecules are loaded with lysosomal products for CD4+ T cell stimulation, macroautophagy supports intracellular antigen processing onto MHC class II molecules.
Christian eMuenz
doaj   +1 more source

Delayed-Type hypersensitivity to latex: Computational prediction of MHC class II epitopes on latex allergens [PDF]

, 2009
Delayed type hypersensitivity to natural rubber latex is rare compared to IgE mediated immediate reactions. Binding of allergens to MHC Class II is a crucial step in the presentation of antigens to CD4+ T Cells responsible for delayed reactions ...
Bell R. Eapen
core   +1 more source

The tammar wallaby major histocompatibility complex shows evidence of past genomic instability [PDF]

, 2011
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Beck, S, Belov, K, Coggill, P, Deakin, JE, Harrow, J, Kaufman, J, Siddle, HV, Whilming, L   +7 more
core   +6 more sources

CIITA (MHC class II transactivator) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on CIITA (MHC class II transactivator), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +1 more source