Results 111 to 120 of about 255,748 (249)

Expressions of HLA Class II Genes in Cutaneous Melanoma Were Associated with Clinical Outcome: Bioinformatics Approaches and Systematic Analysis of Public Microarray and RNA-Seq Datasets

Diagnostics, 2019
Major histocompatibility complex (MHC) class II molecules, encoded by human leukocyte antigen (HLA) class II genes, play important roles in antigen presentation and initiation of immune responses.
Yang-Yi Chen, Wei-An Chang, En-Shyh Lin, Yi-Jen Chen, Po-Lin Kuo   +4 more
doaj   +1 more source

Class I dependence of the development of CD4+ CD8- NK1.1+ thymocytes. [PDF]

, 1994
A small subset of functionally active CD4+ CD8- thymocytes express the NK1.1 marker, as do most CD4-CD8- NK1.1+ thymocytes. Previous studies have failed to implicate a role for major histocompatibility complex (MHC) or related molecules in the selection ...
Coles, M, RAULET, David H.
core  

Expression of Invariant Chain (CD 74) and Major Histocompatibility Complex (MHC) Class II Antigens in the Human Fetus¹ [PDF]

, 2002
Sunil Badve, Charuhas Deshpande, Zhongxue Hua, Lögdberg Lennart   +3 more
openalex   +1 more source

Disease status in human and experimental arthritis, and response to TNF blockade, is associated with MHC class II invariant chain (CD74) isoform expression

, 2022
Felix I. L. Clanchy, Federica Borghese, Jonas Byström, Attila Balog, Henry Penn, Peter C. Taylor, Trevor W. Stone, Rizgar A. Mageed, Richard Williams   +8 more
openalex   +1 more source

Regulation of MHC Class II-Peptide Complex Expression by Ubiquitination

Frontiers in Immunology, 2013
MHC class II (MHC-II) molecules are present on antigen presenting cells (APCs) and these molecules function by binding antigenic peptides and presenting these peptides to antigen-specific CD4+ T cells.
Kyung Jin eCho, Paul A. Roche
doaj   +1 more source

Major histocompatibility complex (MHC) fragment numbers alone – in Atlantic cod and in general - do not represent functional variability [version 1; referees: 2 approved, 1 approved with reservations]

F1000Research, 2018
This correspondence concerns a publication by Malmstrøm et al. in Nature Genetics in October 2016. Malmstrøm et al. made an important contribution to fish phylogeny research by using low-coverage genome sequencing for comparison of 66 teleost (modern ...
Johannes M. Dijkstra, Unni Grimholt
doaj   +1 more source

Murine cytomegalovirus degrades MHC class II to colonize the salivary glands.

PLoS Pathogens, 2018
Cytomegaloviruses (CMVs) persistently and systemically infect the myeloid cells of immunocompetent hosts. Persistence implies immune evasion, and CMVs evade CD8+ T cells by inhibiting MHC class I-restricted antigen presentation.
Joseph Yunis, Helen E Farrell, Kimberley Bruce, Clara Lawler, Stine Sidenius, Orry Wyer, Nicholas Davis-Poynter, Philip G Stevenson   +7 more
doaj   +1 more source

Supplementary Data from Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4⁺ Th1 Responses and Potential Use as a Cancer Vaccine

, 2023
Amrita Basu, Gabriella K. Albert, Sabrina Awshah, Jashodeep Datta, Krithika N. Kodumudi, Corey Gallen, Amber Beyer, Keiran S.M. Smalley, Paulo C. Rodrı́guez, Derek R. Duckett, Peter Forsyth, Aixa Soyano, Gary K. Koski, Ricardo Costa, Heather Han, Hatem Soliman, Marie Catherine Lee, Paweł Kaliński, Brian J. Czerniecki   +18 more
openalex   +1 more source

Major histocompatibility complex class I involvement in the rejection of allogeneic erythrocytes in rainbow trout (Oncorhynchus mykiss) [PDF]

, 2003
Major histocompatibility complex genes are thought to be involved in allogeneic graft rejection but not many reports are available on their functional analysis in fish.
Sarder, M.R.I.
core  

Induction of MHC Class I Presentation of Exogenous Antigen by Dendritic Cells Is Controlled by CD4+ T Cells Engaging Class II Molecules in Cholesterol-Rich Domains [PDF]

, 2002
Patrick Machy, Karine Serre, Marjorie Baillet, Lee Leserman   +3 more
openalex   +1 more source