Results 231 to 240 of about 253,649 (335)

Adenosine signaling inhibits CIITA‐mediated MHC class II transactivation in lung fibroblast cells [PDF]

, 2013
Mingming Fang, Jun Xia, Xiaoyan Wu, Hui Kong, Hong Wang, Weiping Xie, Yong Xu   +6 more
openalex   +1 more source

Disease status in human and experimental arthritis, and response to TNF blockade, is associated with MHC class II invariant chain (CD74) isoform expression

, 2022
Felix I. L. Clanchy, Federica Borghese, Jonas Byström, Attila Balog, Henry Penn, Peter C. Taylor, Trevor W. Stone, Rizgar A. Mageed, Richard Williams   +8 more
openalex   +1 more source

Regulation of MHC Class II Gene Expression

Immunobiology, 1995
Reith, Walter, Steimle, Viktor, Durand, Bénédicte, Kobr, M., Mach, Bernard   +4 more
openaire   +3 more sources

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Immunogenetic diversity of MHC class II B-Lβ genes in Brazilian Caipiras (free-range) chickens laying blue eggs. [PDF]

Front Immunol
Costamilan CADVLR, Paludo E, Herkenhoff ME, Pértille F, de Souza ALS, Mendes CR, Dilarri G.   +6 more
europepmc   +1 more source

Diversity and evolution of the MHC class II DRB gene in the Capra sibirica experienced a demographic fluctuation in China. [PDF]

Sci Rep, 2023
Dong PP, Wang RR, Abduriyim S.
europepmc   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Canine intestinal organoids as a platform for studying MHC class II expression in epithelial cells. [PDF]

BMC Mol Cell Biol
Nakazawa M, Nagao I, Ambrosini YM.
europepmc   +1 more source

Enzymatically mediated engineering of multivalent MHC class II–peptide chimeras [PDF]

, 2001
Sofía Casares, Constantin A. Bona, Teodor‐D. Brumeanu   +2 more
openalex   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source