Results 91 to 100 of about 15,444 (261)

Pharmacology and metabolism of anidulafungin, caspofungin and micafungin in the treatment of invasive candidosis - review of the literature

European Journal of Medical Research, 2011
Echinocandins represent the newest class of antifungal agents. Currently, three echinocandins, anidulafungin, caspofungin and micafungin are licensed for clinical use in various indications.
Kofla G, Ruhnke M
doaj   +1 more source

Caspofungin and Polymyxin B Reduce the Cell Viability and Total Biomass of Mixed Biofilms of Carbapenem-Resistant Pseudomonas aeruginosa and Candida spp.

Frontiers in Microbiology, 2020
Pseudomonas aeruginosa and Candida spp. are biofilm-forming pathogens commonly found colonizing medical devices, being mainly associated with pneumonia and bloodstream infections.
Luciana Fernandes, Bruna Nakanishi Fortes, Nilton Lincopan, Kelly Ishida   +3 more
doaj   +1 more source

New cell wall-affecting antifungal antibiotics [PDF]

, 2013
Capítulo 9.Fungi have emerged worldwide as increasingly frequent causes of healthcare-associated infections. Invasive fungal infections can be life-threatening.
Cortés, Juan Carlos G., Durán, Ángel, Ribas, Juan Carlos   +2 more
core   +2 more sources

Inter‐Hospital Spread of Fluconazole‐Resistant C. parapsilosis in Northern Italy: Insights Into Clonal Distribution, Resistance Mechanisms and Biofilm Production

Mycoses, Volume 68, Issue 9, September 2025.
ABSTRACT Background Starting from 2018 onwards, several outbreaks of fluconazole‐resistant C. parapsilosis have been reported in many countries worldwide. Objectives Here we report a retrospective study on C. parapsilosis blood isolates collected over 7 years (2018–2024) in two hospitals in Northern Italy.
Giorgia Palladini, Valentina Lepera, Serena Trubini, Gabriella Tocci, Andrea Zappavigna, Elizabeth Iskandar, Guglielmo Ferrari, Anna Prigitano, Nicola Ferraro, Roberta Schiavo, Fausto Baldanti, Caterina Cavanna, Giuliana Lo Cascio   +12 more
wiley   +1 more source

Cost Analysis of the Use of Voriconazole, Posaconazole and Micafungin in the Primary Prophylaxis of Invasive Fungal Infections in Recipients of Allogeneic Hematopoietic Stem Cell Transplants

Journal of Health Economics and Outcomes Research, 2015
# Objectives Compare the cost of the primary prophylaxis of invasive fungal infections (IFI) with voriconazole, posaconazole, and micafungin in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) in hospitals of the National ...
Santiago Grau, Carlos Solano, Carol García-Vidal, Isidro Jarque, Jon A. Barrueta, Carmen Peral, Irene Rodríguez, Darío Rubio-Rodríguez, Carlos Rubio-Terrés   +8 more
doaj   +1 more source

Portrait of matrix gene expression in Candida glabrata biofilms with stress induced by different drugs [PDF]

, 2018
(1) Background: Candida glabrata is one of the most significant Candida species associated with severe cases of candidiasis. Biofilm formation is an important feature, closely associated with antifungal resistance, involving alterations of gene ...
Henriques, Mariana, Rodrigues, Célia F.
core   +2 more sources

Rezafungin Utilisation in Real Life—FungiScope Results From Europe and the United States

Mycoses, Volume 68, Issue 9, September 2025.
ABSTRACT Background Rezafungin, a novel echinocandin with once‐weekly intravenous dosing, offers potential advantages for outpatient parenteral antifungal therapy (OPAT) in invasive candidiasis (IC). While clinical trial data support its efficacy and safety, real‐world experience remains limited.
Ilana Reinhold, Giovanni Mori, Massimiliano Lanzafame, Alessandro Limongelli, Antonio Vena, Julia Götz, Stilla Bauernfeind, Frank Hanses, Lukas Tometten, Michael Mayer, Ansgar Rieke, Ana Soriano‐Martin, Maricela Valerio, Jose A. Vazquez, Patrick Yue, Laman Rahimli, Nijat Azimli, Ertan Sal, Jon Salmanton‐García, Natalia Vasenda, Rosanne Sprute, Jannik Stemler, Sebastian Wingen‐Heimann, Oliver A. Cornely, Danila Seidel   +24 more
wiley   +1 more source

Coagulation dysfunction events associated with echinocandins: a real-world study from FDA adverse event reporting system (FAERS) database

Thrombosis Journal
Background Echinocandins belong to the fourth generation of antifungals, and there are no systematic studies on their risk in coagulation dysfunction; this study will predict the risk of coagulation dysfunction of echinocandins using the US Food and Drug
Qian Cheng, Ye Wu, Zeyu Yao, Mengling Ouyang, Shupeng Zou, Xuan Shi, Yazheng Zhao, Minghui Sun   +7 more
doaj   +1 more source

The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]

, 2017
Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K, Diaz, Jose J, Jr, Huston, Jared M, May, Addison K, Mazuski, John E, Mollen, Kevin P, Nadler, Evan P, O\u27Neill, Patrick J, Prince, Jose M, Rosengart, Matthew R, Sawyer, Robert G, Tessier, Jeffrey M   +11 more
core   +3 more sources

Evaluating the Prognostic Value of the EQUAL Candida Score and a Nomogram‐Based Approach for Candidaemia‐Related Mortality

Mycoses, Volume 68, Issue 9, September 2025.
ABSTRACT Introduction Candidaemia is a life‐threatening infection with a persistently high mortality rate, despite significant advances in antifungal therapy and supportive care. The European Confederation of Medical Mycology developed the EQUAL Candida Score as a standardised tool to evaluate adherence to guideline‐based management; however, its ...
Elif Mukime Saricaoglu, Melike Inan Hekimoglu, Ezgi Gulten, Irem Akdemir, Gule Cinar, Afife Zeynep Yilmaz, Duygu Ocal, Irem Kar, Kemal Osman Memikoglu, Fugen Yoruk   +9 more
wiley   +1 more source