Results 11 to 20 of about 17,905 (230)

Prospective Study on Prophylactic Micafungin Sodium against Invasive Fungal Disease during Neutropenia in Pediatric & Adolescent Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation

Children, 2022
Background: Invasive fungal diseases (IFDs) increase the mortality rate of patients with neutropenia who receive chemotherapy or have previously undergone hematopoietic stem cell transplantation (HSCT).
Bo-Kyung Kim, Jung-Yoon Choi, Kyung-Taek Hong, Hong-Yul An, Hee-Young Shin, Hyoung-Jin Kang   +5 more
doaj   +2 more sources

Micafungin-induced rhabdomyolysis and myocardial injury: a case report [PDF]

Frontiers in Medicine
An 82-year-old woman with pulmonary aspergillosis developed dark-colored urine, markedly elevated creatine kinase (3,125 U/L) and myoglobin (3884.4 ng/mL), and delayed myocardial injury (high-sensitivity troponin I: 26301.6 pg/mL) on day 2 after ...
Qing Liu, Qin Li
doaj   +2 more sources

Micafungin prophylaxis for acute leukemia patients undergoing induction chemotherapy

BMC Cancer, 2019
Background Micafungin is a well-tolerated and effective prophylactic antifungal agent used in hematologic diseases. In this prospective trial, we evaluated the efficacy and safety of prophylactic micafungin during first induction chemotherapy in patients
Hyunkyung Park, Jeonghwan Youk, Dong-Yeop Shin, Junshik Hong, Inho Kim, Nam Joong Kim, Jeong-Ok Lee, Soo-Mee Bang, Sung-Soo Yoon, Wan Beom Park, Youngil Koh   +10 more
doaj   +2 more sources

Successful Management of <i>Candida auris</i> Bloodstream Infection in an Elderly Patient: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Candida auris is an emerging multidrug‐resistant pathogen frequently misidentified by conventional methods, posing diagnostic and infection‐control challenges, particularly in low‐ and middle‐income countries. We report a 74‐year‐old male in Dhaka, Bangladesh, with multiple comorbidities who developed Candidemia.
Chowdhury AH, Rahman T, Islam N, Sadique T, Khan AR, Sen D, Abdullah A, Mondal D, Ahmed D.   +8 more
europepmc   +2 more sources

Ultrastructural and Immunohistochemical Study of Double and Combined Intravitreal Administration of Antifungal Agents in the Retina of New Zealand Albino Rabbits: An Experimental Protocol [PDF]

Journal of Fungi
Introduction: Fungal endophthalmitis (FE) is a rare but serious intraocular inflammatory disorder, resulting from an infection of the vitreous cavity from either endogenous or exogenous components that ultimately results in blindness.
Sofia Karachrysafi, Maria Kourti, Sophia Tsokkou, Despoina Ioannou, Evangelia Kofidou, Georgios Delis, Sotiris Sotiriou, Athanasios Karamitsos, Maria Xioteli, Ioanna Dori, Penelope Anastasiadou, Ioannis Konstantinidis, Dimitrios Kavvadas, Fotios Chatzinikolaou, Anastasia Komnenou, Vasileios Karampatakis, Antonia Sioga, Theodora Papamitsou   +17 more
doaj   +2 more sources

First Report of Fluconazole-Resistant Candida parapsilosis Harbouring the G458S ERG11p Substitution in a Brazilian Hospital. [PDF]

Mycoses
ABSTRACT Background Fluconazole‐resistant Candida parapsilosis is a matter of concern. Objectives To investigate fluconazole resistance among Candida parapsilosis complex isolates from patients admitted to three Brazilian hospitals, and to characterise resistance mechanisms and clonal relatedness. Patients/Methods A total of 76 C.
Gonçalves SS, Maifrede SB, Yäkel E, Peçanha PM, Bessa-Neto FO, Cayô R, Rodrigues AM, Muñoz P, Escribano P, Guinea J.   +9 more
europepmc   +2 more sources

Cost-Effectiveness of Once Weekly Rezafungin for the Treatment of Invasive Candidiasis in the United Kingdom. [PDF]

Mycoses
ABSTRACT Background Invasive candidiasis (IC), life‐threatening fungal infections with high economic burden, are often treated first‐line with daily intravenous echinocandins. A new once weekly echinocandin, rezafungin, demonstrated statistically non‐inferior efficacy and numerically shorter intensive care unit (ICU) stay compared to caspofungin in ...
Muszbek N, Angdembe A, Garcia-Vidal C, Bielicka I, Abrams KR, Tolley K, Ruhnke M, Lebmeier M, Hawkins N, Manamley N, Dickerson S.   +10 more
europepmc   +2 more sources

Micafungin effect on Pseudomonas aeruginosa metabolome, virulence and biofilm: potential quorum sensing inhibitor

AMB Express, 2023
The prevalence of antibiotic resistance in Pseudomonas aeruginosa places a heavy burden on the health care sectors urging the need to find alternative, non-antibiotic strategies. The interference with the P.
Duaa M. Hijazi, Lina A. Dahabiyeh, Salah Abdelrazig, Dana A. Alqudah, A. Al-Bakri   +4 more
semanticscholar   +1 more source

A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombe. [PDF]

PLoS ONE, 2013
Micafungin is a non-reversible inhibitor of 1, 3-β-D-glucan synthase and interferes with fungal cell wall synthesis. Clinically, micafungin has been shown to be efficacious for the treatment of invasive candidiasis and invasive aspergillosis.
Xin Zhou, Yan Ma, Yue Fang, Wugan gerile, Wurentuya Jaiseng, Yuki Yamada, Takayoshi Kuno   +6 more
doaj   +1 more source

Improving the production of the micafungin precursor FR901379 in an industrial production strain

Microbial Cell Factories, 2023
Background Micafungin is an echinocandin-type antifungal agent used for the clinical treatment of invasive fungal infections. It is semisynthesized from the sulfonated lipohexapeptide FR901379, a nonribosomal peptide produced by the filamentous fungus ...
P. Men, Y. Zhou, Li Xie, Xuan Zhang, Wei Zhang, Xuenian Huang, Xuefeng Lu   +6 more
semanticscholar   +1 more source