Results 11 to 20 of about 11,994 (242)

Plasma and Cerebrospinal Fluid Concentrations of Micafungin Administered at High Doses in Critically Ill Infants with Systemic Candidiasis: A Pooled Analysis of Two Studies

Pharmaceuticals, 2023
Background: Neonates may require higher doses of micafungin than adults to reach the therapeutic effect for increased plasma clearance. Only poor and inconclusive data are available still now to support this hypothesis, especially with regard to central ...
Domenico Umberto De Rose, Iliana Bersani, Maria Paola Ronchetti, Fiammetta Piersigilli, Sara Cairoli, Andrea Dotta, Amit Desai, Laura Lynn Kovanda, Bianca Maria Goffredo, Cinzia Auriti   +9 more
doaj   +2 more sources

Species Distribution of Candidemia and Their Susceptibility in a Single Japanese University Hospital: Prior Micafungin Use Affects the Appearance of Candida parapsilosis and Elevation of Micafungin MICs in Non-parapsilosis Candida Species

Journal of Fungi, 2021
Introduction: Micafungin is a recommended echinocandin antifungal agent for candidemia treatment and prophylaxis. However, overuse of echinocandin antifungals may cause resistance.
Yasutaka Sakamoto, Kazuhiro Kawabe, Tomoyo Suzuki, Kayoko Sano, Kazuo Ide, Tetsuta Nishigaki, Yuki Enoki, Kazuaki Taguchi, Hirofumi Koike, Hideaki Kato, Yukiko Sahashi, Kazuaki Matsumoto   +11 more
doaj   +2 more sources

A case of bloodstream co-infection of Saccharomyces cerevisiae and Candida glabrata while using micafungin

BMC Infectious Diseases, 2023
Background Saccharomyces cerevisiae is ubiquitous in the gastrointestinal tract and known as brewer's or baker's yeast. We experienced a case of S. cerevisiae and Candida glabrata co-infectious bloodstream infection.
Kento Furuya, Kenta Ito, Kyohei Sugiyama, Satoshi Tokuda, Hideyuki Kanemoto, Katsuhiko Kamei, Toshio Shimada   +6 more
doaj   +2 more sources

Prospective Study on Prophylactic Micafungin Sodium against Invasive Fungal Disease during Neutropenia in Pediatric & Adolescent Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation

Children, 2022
Background: Invasive fungal diseases (IFDs) increase the mortality rate of patients with neutropenia who receive chemotherapy or have previously undergone hematopoietic stem cell transplantation (HSCT).
Bo-Kyung Kim, Jung-Yoon Choi, Kyung-Taek Hong, Hong-Yul An, Hee-Young Shin, Hyoung-Jin Kang   +5 more
doaj   +2 more sources

Does DHN-Melanin Always Protect Fungi against Antifungal Drugs? The Fonsecaea/Micafungin Paradigm

Microbiology Research, 2022
Several human pathogenic fungi produce melanin. One of its properties during parasitism is the protection against antifungal drugs. This occurs with the agents of chromoblastomycosis, in which DHN-melanin reduces antifungal susceptibility to terbinafine ...
Rowena Alves Coelho, Maria Helena Galdino Figueiredo-Carvalho, Juliana Vitória dos Santos Silva, Dario Correa-Junior, Susana Frases, Rosely Maria Zancopé-Oliveira, Dayvison Francis Saraiva Freitas, Rodrigo Almeida-Paes   +7 more
doaj   +2 more sources

Human Tissue Distribution of Anidulafungin and Micafungin

Antimicrobial Agents and Chemotherapy, 2021
Concentrations of anidulafungin and micafungin were determined in eight different tissues obtained during autopsy of four deceased individuals who had been treated with anidulafungin and of seven who had received micafungin.
J. Marx, R. Welte, Tiziana Gasperetti, P. Moser, M. Joannidis, R. Bellmann   +5 more
semanticscholar   +4 more sources

Micafungin-Induced Suicidal Erythrocyte Death [PDF]

Cellular Physiology and Biochemistry, 2016
Background/Aims: The antifungal drug Micafungin is used for the treatment of diverse fungal infections including candidiasis and aspergillosis. Side effects of Micafungin treatment include microangiopathic hemolytic anemia and thrombocytopenia with ...
Thomas Peter, Rosi Bissinger, Elena Signoretto, Andreas F. Mack, Florian Lang   +4 more
doaj   +5 more sources

Micafungin induced apoptosis in Candida parapsilosis independent of its susceptibility to micafungin [PDF]

Microbial Cell, 2015
We hypothesized that the cell wall inhibitor micafungin (MICA) induces apoptosis in both MICA-susceptible (MICA-S) and MICA–non-susceptible (MICA-NS) Candida parapsilosis.
Fazal Shirazi, Russel E. Lewis, Dimitrios P. Kontoyiannis   +2 more
doaj   +4 more sources

Combination of Systemic and Lock-Therapies with Micafungin Eradicate Catheter-Based Biofilms and Infections Caused by Candida albicans and Candida parapsilosis in Neutropenic Rabbit Models

Journal of Fungi
Vascular catheter-related infections, primarily caused by Candida albicans and Candida parapsilosis, pose significant challenges due to the formation of biofilms on catheters, leading to refractory disease and considerable morbidity.
Ruta Petraitiene, Vidmantas Petraitis, Myo H. Zaw, Kaiser Hussain, Rodolfo J. Ricart Arbona, Emanuel Roilides, Thomas J. Walsh   +6 more
doaj   +2 more sources

Micafungin prophylaxis for acute leukemia patients undergoing induction chemotherapy

BMC Cancer, 2019
Background Micafungin is a well-tolerated and effective prophylactic antifungal agent used in hematologic diseases. In this prospective trial, we evaluated the efficacy and safety of prophylactic micafungin during first induction chemotherapy in patients
Hyunkyung Park, Jeonghwan Youk, Dong-Yeop Shin, Junshik Hong, Inho Kim, Nam Joong Kim, Jeong-Ok Lee, Soo-Mee Bang, Sung-Soo Yoon, Wan Beom Park, Youngil Koh   +10 more
doaj   +2 more sources