Results 61 to 70 of about 11,994 (242)

Risk Factors and Long‐Term Prognosis for Coinfection of Nontuberculous Mycobacterial Pulmonary Disease and Chronic Pulmonary Aspergillosis: A Multicentre Observational Study in Japan

Mycoses, Volume 68, Issue 6, June 2025.
ABSTRACT Background Nontuberculous mycobacterial pulmonary disease (NTM‐PD) is a chronic respiratory infection with increasing prevalence and mortality worldwide. Coinfection with chronic pulmonary aspergillosis (CPA) is a significant complication of NTM‐PD, often complicating treatment and resulting in poor prognosis.
Yasuhiro Tanaka, Shotaro Ide, Takahiro Takazono, Kazuaki Takeda, Naoki Iwanaga, Masataka Yoshida, Naoki Hosogaya, Yusei Tsukamoto, Satoshi Irifune, Takayuki Suyama, Tomo Mihara, Akira Kondo, Tsutomu Kobayashi, Yuichi Fukuda, Eisuke Sasaki, Toyomitsu Sawai, Yasuhito Higashiyama, Kohji Hashiguchi, Minako Hanaka, Toshihiko Ii, Kiyoyasu Fukushima, Kosaku Komiya, Taiga Miyazaki, Kazuhiro Yatera, Koichi Izumikawa, Akitsugu Furumoto, Katsunori Yanagihara, Hiroshi Mukae   +27 more
wiley   +1 more source

Antifungal Resistance Among Candida Species: Diagnostic and Clinical Challenges in Specialized Cancer Care Hospital of Lahore

Journal of Clinical Laboratory Analysis, Volume 39, Issue 9, May 2025.
Consumption of antifungals showed a declining trend, with the highest consumption of oral voriconazole (mean DOT/1000 pt. days 18653.49) and oral fluconazole (mean DOT/1000 pt. days 15258.14). Candida albicans was the most isolated pathogen 768 (53.60%) and among all Candida species, major resistance was found in Candida tropicalis 58 (4.05%).
Zunaira Akbar, Muhammad Aamir, Zikria Saleem, Muhammad Rehan Khan Niazi, Hasan Ejaz, Muharib Alruwaili, Khalid Abosalif   +6 more
wiley   +1 more source

Histological Effects of Intravitreal Injection of Antifungal Agents in New Zealand White Rabbits: An Electron Microscopic and Immunohistochemical Study

Pharmaceuticals, 2020
Fungal endophthalmitis is a serious and vision-threatening infection which requires an immediate and effective treatment approach. Our research aims to elucidate the histological effects of the intravitreal injection of the maximum safe dosage of ...
Sofia Karachrysafi, Antonia Sioga, Anastasia Komnenou, Athanasios Karamitsos, Maria Xioteli, Ioanna Dori, Georgios Delis, Evangelia Kofidou, Penelope Anastasiadou, Sotiris Sotiriou, Vasileios Karampatakis, Theodora Papamitsou   +11 more
doaj   +1 more source

Caspofungin Inhibits Mixed Biofilms of Candida albicans and Methicillin-Resistant Staphylococcus aureus and Displays Effectiveness in Coinfected Galleria mellonella Larvae

Microbiology Spectrum, 2021
Candida albicans and Staphylococcus aureus are pathogens commonly isolated from bloodstream infections worldwide. While coinfection by both pathogens is associated with mixed biofilms and more severe clinical manifestations, due to the combined ...
Gaby Scheunemann, Bruna N. Fortes, Nilton Lincopan, Kelly Ishida   +3 more
doaj   +1 more source

Candida vulturna, the Next Fungal Menace? A Narrative Review

Mycoses, Volume 68, Issue 5, May 2025.
ABSTRACT Introduction The yeast Candida vulturna is a member of the Candida haemulonii species complex, like its close relative Candida auris. Members of this species complex, including C. vulturna, often display reduced susceptibility to one or more antifungal classes. Human invasive infections by C.
Ritika Harchand, Bram Spruijtenburg, Eelco F. J. Meijer, Theun de Groot, Shivaprakash M. Rudramurthy, Jacques F. Meis   +5 more
wiley   +1 more source

Yenidoğanlarda Mikafungin Kullanımı Sonuçları [PDF]

Mikrobiyoloji Bulteni, 2019
Invasive candidiasis is a common and serious infection in premature newborns. Preventing and treating fungal infections is very important to improve the prognosis of premature infants. Fluconazole and amphotericin B are used as the first choice in the treatment of invasive fungal infections of the newborns. In some cases, fluconazole and amphotericin B
Koksal, Nilgun, YEŞİL, EDANUR, ÇELEBİ, SOLMAZ, Hacimustafaoglu, MUSTAFA KEMAL, Cakir, SALİH ÇAĞRI, ÖZKAN, HİLAL, Dorum, Bayram Ali   +6 more
openaire   +3 more sources

FTNIR Spectrometry of Micafungin Sodium Quality

Contact in context, 2022
Intra-lot and inter-lot variability in the spectra of micafungin was detected in the Drug Quality Study (DQS) using Fourier transform near-infrared spectrometry (FTNIR). Two vials of 6 vials sampled from Fresenius Kabi lot ACP106 appeared 7.9 and 14.0 standard deviations (SDs) from the center of the rest of the vials on the DQS FTNIR screening assay ...
James T, Isaacs, Philip J, Almeter, Bradley S, Henderson, Aaron N, Hunter, Thomas L, Platt, Robert A, Lodder   +5 more
openaire   +2 more sources

Pharmacology and metabolism of anidulafungin, caspofungin and micafungin in the treatment of invasive candidosis - review of the literature

European Journal of Medical Research, 2011
Echinocandins represent the newest class of antifungal agents. Currently, three echinocandins, anidulafungin, caspofungin and micafungin are licensed for clinical use in various indications.
Kofla G, Ruhnke M
doaj   +1 more source

Invasive Fungal Disease Associated With Targeted Agents for Acute Myeloid Leukaemia: A Systematic Review

eJHaem, Volume 6, Issue 2, April 2025.
ABSTRACT Objective To examine the incidence of invasive fungal disease (IFD) in patients receiving targeted agents for acute myeloid leukaemia (AML). Methods Literature for this systematic review was identified through a PubMed search in April 2024, using AML, IFD and targeted therapy terms.
Samir Agrawal, Anjaneya Bapat, Christopher P. Eades, Shreyans Gandhi   +3 more
wiley   +1 more source

Review of the pharmacology and clinical studies of micafungin

Drug Design, Development and Therapy, 2009
Micafungin, like other members of the echinocandin class, has a unique mechanism of action that inhibits the synthesis of 1,3-beta-D glucans in the fungal cell wall. It has been approved for treatment of esophageal candidiasis, invasive candidiasis including candidemia, and for prophylaxis of Candida infections in patients undergoing hematopoietic stem
Alison M. Bormann, Vicki A Morrison
openaire   +4 more sources