Results 61 to 70 of about 17,905 (230)
Human Tissue Distribution of Anidulafungin and Micafungin
Antimicrobial Agents and Chemotherapy, 2021 Concentrations of anidulafungin and micafungin were determined in eight different tissues obtained during autopsy of four deceased individuals who had been treated with anidulafungin and of seven who had received micafungin.
J. Marx +5 more
semanticscholar +1 more source
Comparative population plasma and tissue pharmacokinetics of micafungin in critically ill patients with severe burn injuries and patients with complicated intra-abdominal infection [PDF]
, 2016 Severely burned patients have altered drug pharmacokinetics (PKs), but it is unclear how different they are from those in other critically ill patient groups.
Agrifoglio, A. +8 more
core +2 more sources
PHARMACOECONOMIC ANALYSIS OF MICAFUNGIN USING IN THE TREATMENT OF INVASIVE CANDIDIASIS IN NEWBORNS
Педиатрическая фармакология, 2011 Invasive candidiasis is a common cause of neonatal sepsis, especially in children with very low birth weight. This study, for the first time in the world of medical research, shows the results of the clinico-economical expertise of using micafungin to ...
A.S. Kolbin +3 more
doaj +2 more sources
Phenomenon of Dip Effect in Antifungal Susceptibility Testing of Candida tropicalis by using MIC Testing Strips against Echinocandins [PDF]
Journal of Clinical and Diagnostic ResearchMinimum Inhibitory Concentration (MIC) of an antifungal is the minimum concentration that completely inhibits the visible growth of fungi under regulated, uniform and consistent in-vitro conditions.
Sujata lall, Vivek Bhat
doaj +1 more source
Pitfalls associated with the use of molecular diagnostic panels in the diagnosis of cryptococcal meningitis [PDF]
, 2017 We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular ...
Burnham, Carey-Ann +5 more
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp +6 more
wiley +1 more source
Journal of Fungi, 2020 Rezafungin is a next-generation echinocandin that has favorable pharmacokinetic properties. We compared the occurrence of paradoxical growth (PG) and trailing effect (TE) characteristics to echinocadins with rezafungin, caspofungin, micafungin and ...
Zoltán Tóth +9 more
semanticscholar +1 more source
Echinocandins – structure, mechanism of action and use in antifungal therapy
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 With increasing number of immunocompromised patients as well as drug resistance in fungi, the risk of fatal fungal infections in humans increases as well.
Mateusz Szymański +4 more
doaj +1 more source
Bloodstream yeast infections: a 15-month survey [PDF]
, 2009 A 15-month survey of 412 bloodstream yeast isolates from 54 Belgian hospitals was undertaken. Candida albicans was the most common species (47.3%) followed by C. glabrata (25.7%), C. parapsilosis (8.0%), C. tropicalis (6.8%) and Saccharomyces cerevisiae (
Detandt, M +3 more
core +1 more source
VIEW, EarlyView.Pulmonary fungal infections are life‐threatening complications in lung cancer patients, posing significant challenges in clinical management. To address this, we developed machine learning tools that translate routine electronic health record data into actionable insights for diagnosing infections and assessing prognosis.
Hongwei Meng +14 more
wiley +1 more source