Results 191 to 200 of about 54,165 (230)

Genetic background sets the trajectory of cancer evolution

open access: yes
Aitken SJ   +30 more
europepmc   +1 more source

Substrain divergence in C3H inbred mice

Behavior Genetics, 1988
To investigate substrain divergence in the highly inbred C3H strain, we studied the C3H/HeJ, C3H/HeJ//Bkl, C3H/He//Han, and C3H/HeJ//Hd strains. The Hd subline differed from the other three in its lower performance on a two-way active-avoidance learning task, larger infra- and intrapyramidal mossy fiber terminal fields, and rejection of skin grafts ...
B, Heimrich   +3 more
openaire   +3 more sources

Genetic control of hepatocarcinogenesis in C57BL/6J and C3H/HeJ inbred mice

Carcinogenesis, 1986
Treatment of newborn male C3H/HeJ mice with N,N-diethyl-nitrosamine (DEN) or N-ethyl-N-nitrosourea (ENU) resulted in the induction of hepatocellular adenomas and carcinomas with a mean number of tumors per animal that was approximately 20- to 50-fold higher than that for similarly treated C57BL/6J male mice.
N R, Drinkwater, J J, Ginsler
openaire   +3 more sources

Differential Effects of Fluoride During Osteoblasts Mineralization in C57BL/6J and C3H/HeJ Inbred Strains of Mice

Biological Trace Element Research, 2014
The behavior of fluoride ions in biological systems has advantages and problems. On one hand, fluoride could be a mitogenic stimulus for osteoblasts. However, high concentrations of this element can cause apoptosis in rat and mouse osteoblasts. Toward an understanding of this effect, we examined the role of sodium fluoride (NaF) in two mouse calvaria ...
Sandra S, Matsuda   +4 more
openaire   +3 more sources

Alveolar Process Anabolic Activity in C3H/HeJ and C57BL/6J Inbred Mice

Journal of Periodontology, 2008
Background: The purpose of this study was to characterize bone activity of the alveolar process in C3H/HeJ (C3H) and C57BL/6J (B6) inbred mice. Based on observations in other animal species, we hypothesized that the bone‐formation rate/bone surface (BFR/BS) is greater in the alveolar process compared to the body of the mandible and that the bone ...
Isaac F, Meta   +3 more
openaire   +3 more sources

Coxsackievirus B3 myocarditis in C3H/HeJ mice: Description of an inbred model and the effect of exercise on virulence

European Journal of Epidemiology, 1989
The effect of forced exercise on the development of coxsackievirus B3 myocarditis in inbred C3H/HeJ mice was studied. Four groups of mice (30 per group) were formed: infected-exercised (Group I); infected-unexercised (Group II); uninfected-exercised (Group III); and uninfected-unexercised (Group IV). Infected mice were inoculated intraperitoneally with
R J, Kiel   +4 more
openaire   +3 more sources

Increased Expression of Intracisternal A-Particle RNA in Regenerated Myeloid Cells after X Irradiation in C3H/He Inbred Mice

Radiation Research, 2000
Myeloid Cells after X Irradiation in C3H/He Inbred Mice. Myeloid leukemia cells were derived from regenerated hematopoietic cells damaged by sublethal doses of X radiation in C3H/He inbred mice. We previously found that within the genome of the myeloid leukemia cells, a retrotransposon, the intracisternal A-particle (IAP) element, is integrated. Levels
H, Ishihara   +3 more
openaire   +3 more sources

Identification of inbred strains of mice: II. Characterization of different substrains of the C3H strain.

The Journal of heredity, 1978
Substrains of inbred C3H mice differ significantly in their genetic constitution with respect to biochemical markers, skin grafting, and skeletal variations. The presence of such discrepancies among substrains poses a problem when comparing conclusions based on experiments done in different substrains.
Krog, H, Moutier, R
openaire   +3 more sources

Studies of Trypanosoma Cruzi Clones in Inbred Mice

The American Journal of Tropical Medicine and Hygiene, 1983
Two single-cell-isolate cloned stocks of the Sylvio-X10 strain, recovered from an acute human Trypanosoma cruzi infection, were used to infect C3H/HEN mice. The Sylvio-X10/4 clone produced a chronic infection in mice; clone Sylvio-X10/7 produced an acute lethal infection under identical experimental conditions.
M, Postan, J A, Dvorak, J P, McDaniel
openaire   +3 more sources

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