Results 141 to 150 of about 210,454 (234)

Of Bombs and Boats and Mice and Men: A Random tour through some scaling laws [PDF]

open access: yesarXiv, 2012
A trip through some of the standard examples of dimensional analysis and scaling, with further thoughts on yacht prices, growing up, mice, bears and marsupials.
arxiv  

Does tolerance to ethanol-induced ataxia explain the sensitized response to ethanol?

open access: yesFrontiers in Psychiatry
Under conditions of repeated exposure to ethanol, a sensitized locomotor stimulant response develops in some strains of mice. It has been hypothesized that the sensitized response is a consequence of tolerance development to the sedative/incoordinating ...
Cheryl Reed   +4 more
doaj   +1 more source

Comparison of Adult Hippocampal Neurogenesis and Susceptibility to Treadmill Exercise in Nine Mouse Strains

open access: yesNeural Plasticity, 2017
The genetic background of mice has various influences on the efficacy of physical exercise, as well as adult neurogenesis in the hippocampus. In this study, we investigated the basal level of hippocampal neurogenesis, as well as the effects of treadmill ...
Jong Whi Kim   +7 more
doaj   +1 more source

Detection and Tracking of Multiple Mice Using Part Proposal Networks [PDF]

open access: yesarXiv, 2019
The study of mouse social behaviours has been increasingly undertaken in neuroscience research. However, automated quantification of mouse behaviours from the videos of interacting mice is still a challenging problem, where object tracking plays a key role in locating mice in their living spaces.
arxiv  

Surrogate-based Optimization using Mutual Information for Computer Experiments (optim-MICE) [PDF]

open access: yesarXiv, 2019
The computational burden of running a complex computer model can make optimization impractical. Gaussian Processes (GPs) are statistical surrogates (also known as emulators) that alleviate this issue since they cheaply replace the computer model. As a result, the exploration vs.
arxiv  

The same but different: impact of animal facility sanitary status on a transgenic mouse model of Alzheimer's disease [PDF]

open access: yesarXiv
The gut-brain axis has emerged as a key player in the regulation of brain function and cognitive health. Gut microbiota dysbiosis has been observed in preclinical models of Alzheimer's disease and patients. Manipulating the composition of the gut microbiota enhances or delays neuropathology and cognitive deficits in mouse models.
arxiv  

Effect of dietary cholesterol and taurocholate on cholesterol 7 alpha-hydroxylase and hepatic LDL receptors in inbred mice

open access: yesJournal of Lipid Research, 1993
Compared to BALB/c mice, inbred C57BL/6 mice are more susceptible to developing fatty streak atherosclerotic lesions when fed a cholesterol-rich diet containing taurocholate. We examined the metabolic basis for the taurocholate requirement.
S Dueland   +5 more
doaj  

Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis

open access: yesBone Research
Rheumatoid arthritis (RA) is an autoimmune disease. Early studies hold an opinion that gut microbiota is environmentally acquired and associated with RA susceptibility.
Hongzhen Chen   +17 more
doaj   +1 more source

Effects of restraint stress on the regulation of hippocampal glutamate receptor and inflammation genes in female C57BL/6 and BALB/c mice

open access: yesNeurobiology of Stress, 2019
The two strains of inbred mice, BALB/c and C57BL/6, are widely used in pre-clinical psychiatry research due to their differences in stress susceptibility.
Joshua McWhirt   +3 more
doaj  

Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants[S]

open access: yesJournal of Lipid Research, 2018
Diet1 modulates intestinal production of the hormone, fibroblast growth factor (FGF)15, which signals in liver to regulate bile acid synthesis. C57BL/6ByJ mice with a spontaneous Diet1-null mutation are resistant to hypercholesterolemia compared with ...
Jessica M. Lee   +7 more
doaj  

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