Results 141 to 150 of about 350,782 (186)

Identification of vacuolar autophagic aggregates in the skeletal muscles of inbred C57BL/6NCrl mice

Laboratory Animals, 2023
A comprehensive pathological analysis of inbred strains is essential to define strain-specific spontaneous lesions and to understand whether a specific phenotype results from experimental intervention or reflects a naturally occurring disease. This study aimed to report and describe a novel condition affecting the skeletal muscles of an inbred C57BL ...
De Biase D., Pagano T. B., Malanga D., Russo V., Piegari G., d'Aquino I., Iovane V., Scarfo M., Papparella S., Wojcik S., Paciello O.   +10 more
  +7 more sources

Outbred, UM-HET3 mice have greater metabolic and arterial function than inbred, C57BL/6J mice

Physiology, 2023
In recent years, UM-HET3 mice have become more commonly used in biomedical research. UM-HET3 mice are an outbred, genetically diverse strain of mice that is produced by crossing four inbred strains: BALB/cByJ, C57BL/6J, C3H/HeJ, and DBA/2J. Notably, the UM-HET3 strain is used by the National Institute on Aging Interventions Testing Program to ...
Daniel Machin, Jennifer Berg Sen, Zhuoxin Li, Mostafa Sabouri, Christina Deacon, Joseph Bernardo, Xiangyu Zheng   +6 more
openaire   +1 more source

Maternal Behavior in Female C57BL/6J and DBA/2J Inbred Mice

Physiology & Behavior, 1999
Inbred strains of mice exhibit different patterns of maternal behavior, providing material for studies of genetic influences on the expression of maternal behavior. Beginning 1 day after birth, maternal behavior was recorded daily for 14 days in the first and second litters of C57BL/6J (B6) and DBA/2J (D2) mothers.
R E, Brown, W B, Mathieson, J, Stapleton, P E, Neumann   +3 more
openaire   +2 more sources

Alveolar Process Anabolic Activity in C3H/HeJ and C57BL/6J Inbred Mice

Journal of Periodontology, 2008
Background: The purpose of this study was to characterize bone activity of the alveolar process in C3H/HeJ (C3H) and C57BL/6J (B6) inbred mice. Based on observations in other animal species, we hypothesized that the bone‐formation rate/bone surface (BFR/BS) is greater in the alveolar process compared to the body of the mandible and that the bone ...
Isaac F, Meta, Soledad A, Fernandez, Parul, Gulati, Sarandeep S, Huja   +3 more
openaire   +2 more sources

Complete sequence of a hepatic cirrhosis inbred C57BL/6 mice model mitochondrial genome

Mitochondrial DNA Part A, 2014
In the present work we undertook the complete mitochondrial genome sequencing of an important hepatic cirrhosis model inbred C57BL/6 strain for the first time. Its mitogenome was 16,312 bp and coding 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes. A total of 96 SNPs were examined when compared to reference BN sequence.
Xiao-Ling, Jiang, Qiao, Feng, Wei-Hong, Li, Min, Xu, Jun-Sheng, Kang, Li-Xin, Wei   +5 more
openaire   +2 more sources

Casein and 3-methylcholanthrene carcinogenesis in inbred C57BL/6Os female mice.

Journal of the National Cancer Institute, 1977
Groups of inbred C57BL/6Os female mice were subjected to one of the following -reatments: 1) subamyloidogenic administration of sodium caseinate (C group); 2) four intragastric intubations of 0.25 mg 3-methylcholanthrene (MCA) (MCA group); 3) a sodium caseinate injection followed by MCA (C-MCA group); or 4) MCA followed by a soidum caseinate injection (
openaire   +3 more sources

Characterization of cortical spindles in DBA/2 and C57BL/6 inbred mice

Brain Research Bulletin, 1984
Continuous twenty-four hour EEG recordings were conducted on freely-moving DBA/2 and C57BL/6 inbred mice. No brief spindle episodes (BSEs: 6-7 cps, 1-5 sec duration, high amplitude spindle bursts) were seen in the waking EEG of C57BL/6 mice. BSEs were a conspicuous element of the EEG during active waking (AW) and quiet waking (QW) in DBA/2 mice.
openaire   +2 more sources

Large deletion on the Y-chromosome long arm (Yq) of C57BL/6JBomTac inbred mice

Mammalian Genome, 2016
The Y-chromosome of mice has a crucial role in sex determination, gender ratio equilibrium as well as male fertility, and is moreover involved in behavioral, immunological, and cardiovascular traits. During routine short tandem repeat genotyping of C57BL/6 substrains, a unique deletion on the Y-chromosome long arm of males from the commercially ...
Melina, Fischer, Nadezda, Kosyakova, Thomas, Liehr, Peter, Dobrowolski   +3 more
openaire   +2 more sources

Complete mitochondrial genome sequence and mutations of the rhinosinusitis model inbred C57BL/6 mice strain

Mitochondrial DNA Part A, 2015
In the present work, we undertook the complete mitochondrial genome sequencing of an important rhinosinusitis model inbred rat strain for the first time. The total length of the mitogenome was 16,308 bp. It harbored 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes, and 1 non-coding control region (D-loop region).
Yizhou, Qiu, Xuzhang, Jiao, Xiulian, Li, Tiejun, Yuan   +3 more
openaire   +2 more sources

Quantitative trait loci that control body weight in DDD/Sgn and C57BL/6J inbred mice

Mammalian Genome, 2016
Inbred DDD/Sgn mice are heavier than inbred C57BL/6J mice. In the present study, we performed quantitative trait loci (QTL) mapping for body weight using R/qtl in reciprocal F2 male populations between the two strains. We identified four significant QTL on Chrs 1, 2, 5, and 17 (proximal region).
Jun-Ichi, Suto, Misaki, Kojima
openaire   +2 more sources