Results 121 to 130 of about 259,574 (259)

The Evolution of Locally Adaptive Chromosome Inversions in Mimulus guttatus

Molecular Ecology, EarlyView.
ABSTRACT Chromosomal inversion polymorphisms are ubiquitous across the diversity of diploid organisms and play a significant role in the evolution of adaptations in those species. Inversions are thought to operate as supergenes by trapping adaptive alleles at multiple linked loci through the suppression of recombination. While there is now considerable
Leslie M. Kollar, Lauren E. Stanley, Sunil K. Kenchanmane Raju, David B. Lowry, Chad E. Niederhuth   +4 more
wiley   +1 more source

Hyper- and hypo-responsiveness to dietary fat and cholesterol among inbred mice: searching for level and variability genes

Journal of Lipid Research, 1995
A concept proposed by Berg (Berg, K. 1989. Arteriosclerosis. 9: I-50-I-58) is that a combination of level and variability genes determine an individual's overall plasma lipid levels and atherosclerotic risk.
E A Kirk, G L Moe, M T Caldwell, J A Lernmark, D L Wilson, R C LeBoeuf   +5 more
doaj  

Cancer Biology Data Curation at the Mouse Tumor Biology Database (MTB) [PDF]

, 2009
Many advances in the field of cancer biology have been made using mouse models of human cancer. The Mouse Tumor Biology (MTB, "http://tumor.informatics.jax.org":http://tumor.informatics.jax.org) database provides web-based access to data on ...
Carol J. Bult, Dale A. Begley, Debra M. Krupke, Janan T. Eppig, Joel E. Richardson, John P. Sundberg, Steven B. Neuhauser   +6 more
core   +2 more sources

Induction of Hepatomas by Thiouracil in Inbred Strains of Mice.

Experimental Biology and Medicine, 1963
SummaryFeeding a diet containing 0.3% of thiouracil (TU) by dry weight for 18 months to a subline of C3H mice produced a nearly 100% incidence of hepatoma in both sexes. Controls given no TU had definite but significantly lower incidence of this tumor. When the inbred strain of mice TM was used, no hepatomas were observed in experimental nor in control
openaire   +3 more sources

Targeting the Microbiota Reverses C‐Section‐Induced Effects on Intestinal Permeability, Microbiota Composition, and Amygdala Gene Expression in the Mouse

Neurogastroenterology &Motility, EarlyView.
The study investigated the impact of the delivery method on the microbiome in mice, revealing increased intestinal permeability and altered gene expression in Caesarean section (CS)‐born mice compared to vaginal birth (VB) mice. Administration of Bifidobacterium breve or GOS/FOS partially mitigated these effects, suggesting targeted microbiota ...
Ana Paula Ventura Silva, Gerard M. Moloney, Ana Marta Sequeira, Marta Liber, Thomaz Bastiaanssen, Kieran Rea, Patrick Fitzgerald, Anna Golubeva, Maria Rodriguez‐Aburto, Ingrid B. Renes, Jan Knol, Timothy Dinan, John F. Cryan   +12 more
wiley   +1 more source

Immunomodulation of salivary gland function due to cancer therapy

Oral Diseases, EarlyView.
Abstract Functional salivary glands (SG) are essential for maintaining oral health, and salivary dysfunction is a persistent major clinical challenge. Several cancer therapies also have off‐target effects leading to SG dysfunction. Recent advances highlight the role of SG immune populations in homeostasis, dysfunction and gland regeneration.
Ana C. Costa‐da‐Silva, Carlos U. Villapudua, Matthew P. Hoffman, Marit H. Aure   +3 more
wiley   +1 more source

Inherent and antigen-induced airway hyperreactivity in NC mice

Allergology International, 1999
In order to clarify the airway physiology of NC mice, the following experiments were carried out. To investigate inherent airway reactivity, we compared tracheal reactivity to various chemical mediators in NC, BALB/c, C57BL/6 and A/J mice in vitro.
Tetsuto Kobayashi, Toru Miura, Tomoko Haba, Miyuki Sato, Masao Takei, Isao Serizawa   +5 more
doaj   +1 more source

Maize leaf yellowing gene ZmCAAX modulates growth and drought resistance by regulating abscisic acid contents through interaction with the ABA biosynthetic enzyme ZmNCED3

Plant Biotechnology Journal, EarlyView.
Summary In maize (Zea mays L.), leaves are essential for photosynthesis and transpiration and leaf yellowing is regulated by carotenoid metabolism, hormonal signalling and environmental factors. However, the molecular mechanisms linking drought stress and leaf yellowing remain poorly understood.
Xiaohu Li, Bin Zhang, Jiyuan Du, Shuai Chen, Yujiao Wang, Qigui Li, Shilin Zhuge, Xinzheng Li, Yongxin Nie, Gaoke Li, Fang Xu, Aiguo Yang, Zhiming Zhang, Haiping Ding   +13 more
wiley   +1 more source

A Candidate Subspecies Discrimination System Involving a Vomeronasal Receptor Gene with Different Alleles Fixed in \u3ci\u3eM. m. domesticus\u3c/i\u3e and \u3ci\u3eM. m. musculus\u3c/i\u3e [PDF]

, 2010
Assortative mating, a potentially efficient prezygotic reproductive barrier, may prevent loss of genetic potential by avoiding the production of unfit hybrids (i.e., because of hybrid infertility or hybrid breakdown) that occur at regions of secondary ...
Karn, Robert C., Laukaitis, Christina M., Young, Janet M.   +2 more
core   +1 more source

Technical considerations and review of urinary microRNAs as biomarkers for chronic kidney disease in dogs and cats

Veterinary Clinical Pathology, EarlyView.
Abstract MicroRNAs (miRNAs or miRs) are small, non‐coding RNAs that play a crucial role in gene regulation, making them potential biomarkers for various diseases. In the field of veterinary medicine, there is a growing interest in exploring the diagnostic and therapeutic potential of miRNAs in kidney diseases affecting dogs and cats.
Candice P. Chu, Mary B. Nabity
wiley   +1 more source