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Quiet mutations in inbred strains of mice
Trends in Molecular Medicine, 2007The year 2009 is the 100th anniversary of the founding of the first inbred strain of mouse, called DBA. During the last 100 years, inbred strains have proved their value for biomedical research and the number of such strains has mushroomed to over 450, each with different genotypic and phenotypic characteristics and useful for the study of disease and ...
James C, Stevens +3 more
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Antibody Production in Inbred Strains of Mice
The Journal of Immunology, 1953Summary Based on tests involving the use of 5 inbred strains of mice, evidence is presented which indicates that there is genetic variation in the ability of the mouse to produce demonstrable circulating antibody to either egg albumin or pneumococcus polysaccharide.
Fink, M A, Quinn, V A
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Cd‐metallothionein nephrotoxicity in inbred strains of mice
Journal of Toxicology and Environmental Health, 1992Genetic differences in the acute hepatic and testicular toxicity of Cd occur among different strains of mice. However, it is not known whether genetic variation to the renal damage caused by Cd-metallothionein (CdMT) exists. Therefore, male mice of the C3H/HeJ, C57/Bl10, CBA/CA, and DBA/2J strains, previously shown to differ in hepatic and testicular ...
L E, Sendelbach +3 more
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Heterohemoantibodies in Inbred Strains of Mice
The Journal of Immunology, 1954Summary Titers of immune hemoantibodies in mice of 10 inbred strains revealed characteristic patterns for each strain, with considerable variations between strains. The possible role of genetic, metabolic, and hormonal factors in relation to this difference in response of mice to immunization with hemoantigens was discussed.
Kurt Stern, Israel Davidsohn
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Handedness in mice: Comparison across eleven inbred strains
Behavior Genetics, 1991Screening for handedness was performed in 11 inbred strains of mice. Direction and degree of handedness were measured for both males and females in each strain. The data show that there are almost as many right- as left-handed subjects and no strain could be classified as right- or left-handed.
P, Signore +4 more
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Atheromata in an inbred strain of mice
Journal of Atherosclerosis Research, 1969Summary Male C57BL/6J inbred mice started on a high-fat, high-cholesterol diet at age 5–6 weeks survived well (100 % alive after 25 weeks) on the diet provided they were introduced to it gradually. All animals on the diet at least 5 weeks showed marked incorporation of fat into the subendothelial cells and in 7/8 the cells were swollen enough to be ...
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Evolution in Inbred Strains of Mice Appears Rapid
Science, 1985Genetic variation at 97 loci in ten commonly used inbred strains of mice is greatly in excess of that expected under current assumptions. Evidence against all of the readily apparent explanations is presented and the possibility of early selection for heterozygosity or of conversion is suggested.
W M, Fitch, W R, Atchley
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Mating behaviour of two inbred strains of mice
Animal Behaviour, 1966Summary Observations were made of the mating patterns of males from two inbred strains, ST/J and CBA/J, with females from both of these strains. Experiment I involved single males that were housed separately, while experiment II involved inter-strain pairs of males that were housed together. In three out of the four possible situations, the ST males
Levine, L, Barsel, G E, Diakow, C A
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1979
Inbred mice have been used more extensively than those of any other species of laboratory mammal. A total of about 230 strains are listed here, but some of the more widely used strains have become divided into sublines among which there are detectable genetic differences. Some strains are recorded in the literature but are now extinct.
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Inbred mice have been used more extensively than those of any other species of laboratory mammal. A total of about 230 strains are listed here, but some of the more widely used strains have become divided into sublines among which there are detectable genetic differences. Some strains are recorded in the literature but are now extinct.
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Hypothalamic self-stimulation in three inbred strains of mice
Brain Research, 1974Abstract Male mice from 3 inbred strains (DBA/2 Orl, BALB/c Orl and C57 BL/6 Orl) were implanted with a bipolar electrode in the hypothalamus and tested for self-stimulation. The 3 strains differed in performances: the BALB/c mice showed higher scores than the DBA/2 mice which themselves showed higher rates than the C57 BL/6 mice.
Cazala, P, Cazals, Y, Cardo, B
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