Results 71 to 80 of about 1,878,072 (249)
A novel hairless highly immunodeficient mice model optimized for in vivo imaging
Laboratory Animal ResearchBackground In vivo imaging is one of the analytical technologies that has been rapidly growing in demand in recent years to non-invasively observe the behavior of molecules such as genes and proteins in vivo and perform quantitative and qualitative ...
Kouki Matsuda +4 more
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Cancer Biology & Medicine, 2009 OBJECTIVE To investigate whether small hairpin RNA (shRNA) targeting Bcl-2 mRNA could inhibit the growth of lymphoma transplanted subcutaneously in nude mice.METHODS Recombinant Bcl-2 shRNA expression vector with green fluorescence protein (GFP ...
Dongmei HE, Baoying FANG, Yangqiu LI
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Южно-Российский онкологический журнал, 2020 The article has a problematic scripting nature. At the present stage, in addition to objective factors that make it difficult to create adequate experimental models of human oncogenesis, there is a significant backlog of domestic science in the ...
G. V. Zhukova +3 more
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Advanced Materials Technologies, EarlyView.A collagen‐based gut‐on‐chip model replicates the intestinal extracellular matrix, supporting villi‐like structures, tight junctions, and mucin production. This biomimetic platform enables rapid epithelial differentiation and functional barrier formation.
Fernanda López García +4 more
wiley +1 more source
Isolation and Identification of Staphylococcus xylosus in Nude Mice with Squamous Skin Scurfs
Shiyan dongwu yu bijiao yixueObjective To isolate pathogenic bacteria from the skin of a nude mouse exhibiting squamous skin scurfs, and perform bacterial identification, traceability analysis, and pathogenicity studies to provide a new approach for the diagnosis of pathogens in ...
KONG Zhihao +6 more
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HETEROTRANSPLANTATION OF HUMAN NEOPLASMS IN NUDE MICE
The Keio Journal of Medicine, 1975 Heterotransplantation of human neoplastic tissue was investigated in the congenitally athymic mice, nude mice, BALB/c-nu/nu, kept in SPF condition within vinyl isolator.At present, 23 out of 32 established cell lines of various malignant neo plasm, originated from the lung, uterine cervix, endometrium, breast, cholan gioma, neuroblastoma, osteosarcoma ...
Ueyama, Y +3 more
openaire +3 more sources
Advanced Science, EarlyView.Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin +20 more
wiley +1 more source
Cell Transplantation, 2005 Although hepatocyte transplantation is a promising therapy for acute liver failure in human, there is still a lack of animal models suffering from hepatic injury in which the benefits of hepatocyte transplantation could be evaluated solely, without the ...
Arnaud Gandillet +8 more
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Advanced Science, EarlyView.In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu +7 more
wiley +1 more source
Gastroenterology Research and Practice, 2017 A mouse gastric cancer model is an important tool for studying the mechanisms of gastric cancer. To establish subcutaneously implanted tumors, MKN-45 cell suspensions and tumor tissues were implanted into the middle of the right armpit of nude mice.
Yin Zhu +7 more
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