Results 51 to 60 of about 1,878,072 (249)

Realization of malignant potential of human glioblastoma mitochondria in immunodeficient animals

Исследования и практика в медицине, 2023
Purpose. Obtaining extracranial diffuse tumor foci of glioblastoma in Balb/c Nude mice by implantation of mitochondria isolated from human glioblastoma.Material and methods. Human glioblastoma mitochondria were isolated using differential centrifugation in
O. I. Kit, E. M. Frantsiyants, A. I. Shikhlyarova, I. V. Neskubina   +3 more
doaj   +1 more source

Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy

Advanced Healthcare Materials, EarlyView.
This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato, Hiroki Ohta, Naoki Takakura, Kentaro Kasa, Teppei Komatsu, Dai Kejia, Misato Yoshioka, Hirotaka James Okano, Hiroaki Onoe   +8 more
wiley   +1 more source

Improved Xenogenic Hepatocyte Implantation into Nude Mouse Liver Parenchyma with Acute Liver Failure when Followed by Repeated Anti-Fas Antibody (Jo2) Treatment

Cell Transplantation, 2008
Hepatocyte transplantation is a promising therapy for acute liver failure in humans. Recently, we succeeded in inducing various acute and chronic liver failures in nude mice.
Isabelle Vidal, Nadège Blanchard, Eliane Alexandre, Arnaud Gandillet, Marie-Pierre Chenard-Neu, Frank Staedtler, Martin Schumacher, Philippe Bachellier, Daniel Jaeck, Huseyin Firat, Bruno Heyd, Lysiane Richert   +11 more
doaj   +1 more source

Costunolide induces mitochondria-mediated apoptosis in human gastric adenocarcinoma BGC-823 cells

BMC Complementary and Alternative Medicine, 2019
Background Costunolide, a sesquiterpene lactone extracted from Radix Aucklandiae, has the activity against multiple cancers. However, the effect of costunolide on gastric cancer (GC) have remained to be ambiguous.
Zhanpeng Yan, Tingting Xu, Zhentao An, Ying Hu, Wanzhen Chen, Jinxia Ma, Changle Shao, Fangshi Zhu   +7 more
doaj   +1 more source

Oxygels: Tunable Phosphorescent Hydrogels for Cherenkov‐Excited Luminescence Imaging (CELI) of Oxygen

Advanced Healthcare Materials, EarlyView.
Biocompatible hydrogels with covalently embedded near‐infrared phosphorescent probes enable local tissue pO2 quantification by means of Cherenkov‐excited luminescence imaging (CELI), where optical excitation occurs within tissues upon irradiation with high‐energy electron beams.
Simin Belali, Marien Iliza Ochoa Mendoza, Matthew S. Reed, Danylo Mykhalchuk, Annemarie Lang, Joel D. Boerckel, Brian W. Pogue, Sergei A. Vinogradov   +7 more
wiley   +1 more source

Effects of different combined regimens of cisplatin, metformin, and quercetin on nasopharyngeal carcinoma cells and subcutaneous xenografts

Scientific Reports, 2021
Cisplatin, metformin, and quercetin are all reliable anticancer drugs. However, it is unclear how effective their different combination regimens are on the growth of nasopharyngeal carcinoma cell line Sune-1 and subcutaneous xenograft in nude mice.
Zhongwei Chen, Zhen Zeng, Shanshan Zhu, Ying Zeng, Qihuang Lin, Lianzhong Luo, Xuan Hong   +6 more
doaj   +1 more source

Overcoming Photodynamic Therapy Resistance: GSH‐Responsive AIE Photosensitizer‐Hydroxycamptothecin Nanoliposomes for Extrahepatic Cholangiocarcinoma

Advanced Healthcare Materials, EarlyView.
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu, Tao Peng, Yating Zhang, Juanmei Cao, Birong Wang, Chuxing Chai, Zhiyuan Gao, Yiting Xu, Yifan Jin, Yuqing Wang, Zhuoxia Li, Xu Liu, Tianqi Zhao, Yufan Chen, Weimin Lv, Di Lu, Changzheng Huang, Dan Ding, Jinxiang Zhang, Min Li   +19 more
wiley   +1 more source

Interferon Production in Athymic Nude Mice

Journal of General Virology, 1976
Athymic (homozygous nude) mice of a non-inbred stock had relatively little antiviral activity in their serum compared with normal control mice at 4, 6 and 6.5 h after the intraperitoneal injection of Newcastle disease virus. The antiviral activity in the serum had the characteristics of interferon.
E M, Pantelouris, C R, Pringle
openaire   +2 more sources

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism

Molecular Therapy: Oncolytics, 2019
The antimicrobial peptide cathelicidin inhibits development of colitis-associated colon cancer. However, the role of cathelicidin in colon cancer metastasis remains unknown.
Jiani Wang, Michelle Cheng, Ivy K.M. Law, Christina Ortiz, Mingjun Sun, Hon Wai Koon   +5 more
doaj   +1 more source