Results 31 to 40 of about 1,878,072 (249)

SCARLESS SKIN WOUND HEALING IN FOXN1 DEFICIENT (NUDE) MICE IS ASSOCIATED WITH DISTINCTIVE MATRIX METALLOPROTEINASE EXPRESSION

Matrix Biology, 2011
Similar to mammalian fetuses FOXN1 deficient (nude) mice are able to restore the structure and integrity of injured skin in a scarless healing process by mechanisms independent of the genetic background.
Barbara Gawrońska-Kozak
semanticscholar   +1 more source

Effects of Human Adipose-derived Stem Cells on Cutaneous Wound Healing in Nude Mice.

Annals of Dermatology, 2011
BACKGROUND Despite numerous treatments available for deteriorated cutaneous wound healing such as a diabetic foot, there is still the need for more effective therapy.
S. Lee, J. Lee, K. Cho
semanticscholar   +1 more source

Schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with Trypanosoma cruzi

Memorias do Instituto Oswaldo Cruz, 1992
Congenitally athymic nude Balb/c (nu/nu) and their phenothypically normal adult and neonate littermates (nu/+), the C3H/HeN as well, were intraperitoneally infected with two strains (Y or CL) of Trypanossoma cruzi.
Sylvio Celso Gonçalves da Costa, Kátia da Silva Calabrese   +1 more
doaj   +1 more source

Influence of induced diabetes mellitus on hormonal profile of Lewis lung carcinoma in BALB/c Nude mice

Южно-Российский онкологический журнал, 2023
Purpose of the study. The assessment of diabetes mellitus (DM) effect on levels of sex hormones in tumor and peritumoral tissues in BALB/c Nude mice with Lewis lung carcinoma (LLC).Materials and methods.
E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, A. I. Shikhlyarova, E. I. Surikova, I. V. Neskubina, Yu. A. Pogorelova, L. K. Trepitaki, N. D. Cheryarina   +8 more
doaj   +1 more source

ABNORMAL DEVELOPMENT OF THE THYMUS IN "NUDE" MICE [PDF]

The Journal of Experimental Medicine, 1971
Nude mice bearing grafts of normal thymus reject skin grafts and have low, but higher than usual, lymphocyte counts. Nude bone marrow can successfully repopulate the thymus and thymus-derived areas of lethelly irradiated recipient mice. Attempts to reconstitute nude mice with normal fetal liver failed.
Wortis, H H, Nehlsen, S, Owen, J J
openaire   +2 more sources

Effects of NM-3 on lymphatic vessel density and vascular endothelial growth factor of colon cancer in orthotopic implantation model of a severe combined immune deficiency mice

Gastroenterology Insights, 2010
The molecular mechanisms involved colon cancer tumorigenesis and development of colon cancer remain unclear. The aim of this study is to explore the inhibitive effects of NM-3 on lymphatic vessel density and vascular endothelial growth factor of ...
Jin-Shui Zhu, Zhi-Peng Xu, Jian- Lian Chen, Qiang Zhang, Qiang Zhang, Qun Sun   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Transplantation of mitochondria from human malignant tumor cells as a method of tumor growth formation in the lungs of laboratory animals

Исследования и практика в медицине, 2023
Purpose of the study. Obtaining lung cancer tumors in Balb/c Nude mice by transplantation of mitochondria isolated from human malignant tumors.Materials and methods. Human lung cancer mitochondria were isolated using differential centrifugation on a high-
O. I. Kit, E. M. Frantsiyants, A. I. Shikhlyarova, I. V. Neskubina   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source