Results 21 to 30 of about 151,615 (262)

Effects of cisplatin on photosensitizer-mediated photodynamic therapy in breast tumor-bearing nude mice [PDF]

open access: yesObstetrics & Gynecology Science, 2019
ObjectiveThis study aimed to evaluate the potential effects of cisplatin on photodynamic therapy (PDT) in breast cancer using a breast tumor-bearing mouse model.MethodsIn this study, breast tumor (experimental mammary tumour-6 cell)-bearing nude mice ...
Tae-Gyu Ahn   +3 more
doaj   +1 more source

Detection and elimination of Proteus vulgaris and Klebsiella pneumoniae in nude mice [PDF]

open access: yesBiological Journal of Microorganism, 2021
Introduction: Nude mice are immunodeficient, commonly used model organisms for studying human diseases. Despite the high purchase price and maintenance cost of these animals, few studies have aimed to eradicate inevitable infectious complications which ...
Somayeh Najafi Dorcheh   +5 more
doaj   +1 more source

Characterization of in vivo tumorigenicity tests using severe immunodeficient NOD/Shi-scid IL2Rγnull mice for detection of tumorigenic cellular impurities in human cell-processed therapeutic products

open access: yesRegenerative Therapy, 2015
The contamination of human cell-processed therapeutic products (hCTPs) with tumorigenic cells is one of the major concerns in the manufacturing and quality control of hCTPs.
Shinji Kusakawa   +9 more
doaj   +1 more source

ABNORMAL DEVELOPMENT OF THE THYMUS IN "NUDE" MICE [PDF]

open access: yesThe Journal of Experimental Medicine, 1971
Nude mice bearing grafts of normal thymus reject skin grafts and have low, but higher than usual, lymphocyte counts. Nude bone marrow can successfully repopulate the thymus and thymus-derived areas of lethelly irradiated recipient mice. Attempts to reconstitute nude mice with normal fetal liver failed.
Wortis, H H, Nehlsen, S, Owen, J J
openaire   +2 more sources

Evaluation of Anti-Tumorigenic Effects of Diosmetin against Human Colon Cancer Xenografts in Athymic Nude Mice

open access: yesMolecules, 2019
Colon cancer is the third most common type of cancer in the world. Diosmetin (Dis), a natural O-methylated flavone, has been reported to have anti-cancer effects against different types of cancer.
Sanaz Koosha   +3 more
doaj   +1 more source

Histoplasma capsulatum infection in nude mice [PDF]

open access: yesInfection and Immunity, 1978
Congenitally athymic nude (nu/nu) mice, when injected intraperitoneally with Histoplasma capsulatum, developed a rapidly fatal disseminated infection characterized by heavy parasitization of reticuloendothelial tissues. In contrast, their heterozygous (nu/X) littermates, which possessed a functioning thymus, developed only a low-grade infection which ...
Williams, D M, Graybill, J R, Drutz, D J
openaire   +2 more sources

Local inflammation exacerbates the severity of Staphylococcus aureus skin infection. [PDF]

open access: yesPLoS ONE, 2013
Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S. aureus skin infection, we found that lesion size did not correlate with bacterial burden.
Christopher P Montgomery   +5 more
doaj   +1 more source

Schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with Trypanosoma cruzi

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
Congenitally athymic nude Balb/c (nu/nu) and their phenothypically normal adult and neonate littermates (nu/+), the C3H/HeN as well, were intraperitoneally infected with two strains (Y or CL) of Trypanossoma cruzi.
Sylvio Celso Gonçalves da Costa   +1 more
doaj   +1 more source

Influence of induced diabetes mellitus on hormonal profile of Lewis lung carcinoma in BALB/c Nude mice

open access: yesЮжно-Российский онкологический журнал, 2023
Purpose of the study. The assessment of diabetes mellitus (DM) effect on levels of sex hormones in tumor and peritumoral tissues in BALB/c Nude mice with Lewis lung carcinoma (LLC).Materials and methods.
E. M. Frantsiyants   +8 more
doaj   +1 more source

Effects of NM-3 on lymphatic vessel density and vascular endothelial growth factor of colon cancer in orthotopic implantation model of a severe combined immune deficiency mice

open access: yesGastroenterology Insights, 2010
The molecular mechanisms involved colon cancer tumorigenesis and development of colon cancer remain unclear. The aim of this study is to explore the inhibitive effects of NM-3 on lymphatic vessel density and vascular endothelial growth factor of ...
Jin-Shui Zhu   +5 more
doaj   +1 more source

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