Results 21 to 30 of about 1,878,072 (249)

Athymic nude mice as an experimental model for cancer treatment.

open access: yesPhysiological Research, 2016
Athymic nude mice, a murine strain bearing spontaneous deletion in the Foxn1 gene that causes deteriorated or absent thymus (which results in inhibited immune system with reduction of number of T cells), represent a widely used model in cancer research ...
I. Szadvári, O. Krizanova, Petr Babula
semanticscholar   +1 more source

Best Imaging Time of Near-infrared Fluorescence Imaging for Prostate Cancer Xenografts

open access: yesZhongliu Fangzhi Yanjiu, 2019
Objective To investigate the dynamic characteristics, optimal development time and imaging mechanism of indocyanine green (ICG) in vitro near-infrared fluorescence imaging of subcutaneous xenograft tumor of prostate cancer in nude mice.
XUE Yazhou   +6 more
doaj   +1 more source

Histoplasma capsulatum infection in nude mice [PDF]

open access: yesInfection and Immunity, 1978
Congenitally athymic nude (nu/nu) mice, when injected intraperitoneally with Histoplasma capsulatum, developed a rapidly fatal disseminated infection characterized by heavy parasitization of reticuloendothelial tissues. In contrast, their heterozygous (nu/X) littermates, which possessed a functioning thymus, developed only a low-grade infection which ...
Williams, D M, Graybill, J R, Drutz, D J
openaire   +2 more sources

Effects of cisplatin on photosensitizer-mediated photodynamic therapy in breast tumor-bearing nude mice [PDF]

open access: yesObstetrics & Gynecology Science, 2019
ObjectiveThis study aimed to evaluate the potential effects of cisplatin on photodynamic therapy (PDT) in breast cancer using a breast tumor-bearing mouse model.MethodsIn this study, breast tumor (experimental mammary tumour-6 cell)-bearing nude mice ...
Tae-Gyu Ahn   +3 more
doaj   +1 more source

Thermoneutral housing is a critical factor for immune function and diet-induced obesity in C57BL/6 nude mice

open access: yesInternational Journal of Obesity, 2014
Objectives:Obesity-related cancers represent public health burdens of the first order. Nevertheless, suitable mouse models to unravel molecular mechanisms linking obesity to human cancer are still not available.
K. Stemmer   +8 more
semanticscholar   +1 more source

Characterization of in vivo tumorigenicity tests using severe immunodeficient NOD/Shi-scid IL2Rγnull mice for detection of tumorigenic cellular impurities in human cell-processed therapeutic products

open access: yesRegenerative Therapy, 2015
The contamination of human cell-processed therapeutic products (hCTPs) with tumorigenic cells is one of the major concerns in the manufacturing and quality control of hCTPs.
Shinji Kusakawa   +9 more
doaj   +1 more source

Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating TLR4 Signaling to NFκB, Upregulating Expression of microRNA-21

open access: yesGastroenterology, 2016
Background & Aims Nearly 20% of the global cancer burden can be linked to infectious agents. Fusobacterium nucleatum promotes tumor formation by epithelial cells via unclear mechanisms.
Yongzhi Yang   +19 more
semanticscholar   +1 more source

Evaluation of Anti-Tumorigenic Effects of Diosmetin against Human Colon Cancer Xenografts in Athymic Nude Mice

open access: yesMolecules, 2019
Colon cancer is the third most common type of cancer in the world. Diosmetin (Dis), a natural O-methylated flavone, has been reported to have anti-cancer effects against different types of cancer.
Sanaz Koosha   +3 more
doaj   +1 more source

Listeria monocytogenes infection in nude mice [PDF]

open access: yesInfection and Immunity, 1975
As compared to phenotypically normal (nu/+)NMRI mice showing the typical course of an experimental listeric infection, that of congenitally hypothymic (nude, nu/nu)NMRI mice was found to be characterized from the outset bya chronic trend. During the early phase of the infection, significantly reduced numbers of Listeria monocytogenes were observed in ...
Emmerling, P, Finger, H, Bockemuhl, J
openaire   +2 more sources

Local inflammation exacerbates the severity of Staphylococcus aureus skin infection. [PDF]

open access: yesPLoS ONE, 2013
Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S. aureus skin infection, we found that lesion size did not correlate with bacterial burden.
Christopher P Montgomery   +5 more
doaj   +1 more source

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