Results 1 to 10 of about 151,466 (116)

A novel hairless highly immunodeficient mice model optimized for in vivo imaging [PDF]

open access: yesLaboratory Animal Research
Background In vivo imaging is one of the analytical technologies that has been rapidly growing in demand in recent years to non-invasively observe the behavior of molecules such as genes and proteins in vivo and perform quantitative and qualitative ...
Kouki Matsuda   +4 more
doaj   +2 more sources

Artemether as a modulator of EMT in colorectal cancer: enhancing radiosensitivity and reversing chemo-radiation resistance [PDF]

open access: yesBMC Gastroenterology
Background The efficacy of conventional chemoradiotherapy for colorectal cancer is often limited by resistance, with epithelial-mesenchymal transition being a key mechanism.
Lv Ge   +11 more
doaj   +2 more sources

A study on mechanism of GOLM1 regulating PI3K/AKT/mTOR signaling pathway to promote proliferation, invasion and migration of lung adenocarcinoma cells [PDF]

open access: yesZhongguo aizheng zazhi, 2022
Background and purpose: Golgi membrane protein 1 (GOLM1) plays the role of an oncogene in lung adenocarcinoma (LUAD), however, the effects of GOLM1 on the proliferation, invasion and migration of LUAD cells and its mechanism are not clear yet. This study
ZHU Haipeng, HU Jun, JIANG Min, CAI Ruonan, WANG Junqiao, LI Li
doaj   +3 more sources

Effects of Long-Term Cryopreservation on Fat Grafts: An Experimental Study [PDF]

open access: yesArchives of Aesthetic Plastic Surgery, 2014
Background Although microfat grafting is now used to augment soft tissue, resorption of some amount of fat is inevitable. There are no consistent guidelines for the duration of fat storage.
Hee Jong Lee, Eun Key Kim
doaj   +1 more source

The protection of CoronaVac against the infection of wild‐type SARS‐CoV‐2 (WH‐09) or Omicron variant in nude‐hACE2 mice

open access: yesAnimal Models and Experimental Medicine, 2023
Background Immunocompromised individuals have an increased risk of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and severe outcomes, but we pay less attention to these people.
Kaili Lin   +7 more
doaj   +1 more source

Comparing the MRI appearance of the lymph nodes and spleen in wild-type and immuno-deficient mouse strains. [PDF]

open access: yesPLoS ONE, 2011
The goal of this study was to investigate the normal MRI appearance of lymphoid organs in immuno-competent and immuno-deficient mice commonly used in research.
Vasiliki Economopoulos   +4 more
doaj   +1 more source

Prevalence of Mouse Norovirus in Experimental Mice in Beijing

open access: yesShiyan dongwu yu bijiao yixue, 2023
ObjectiveTo investigate the infection of mouse norovirus (MNV) in experimental mice raised under natural conditions from 19 biological companies in Beijing.MethodsThe mice used in this study were randomly selected from mice produced by 19 companies, and ...
LIU Fangni   +4 more
doaj   +1 more source

NSG Mice Provide a Better Spontaneous Model of Breast Cancer Metastasis than Athymic (Nude) Mice. [PDF]

open access: yesPLoS ONE, 2016
Metastasis is the most common cause of mortality in breast cancer patients worldwide. To identify improved mouse models for breast cancer growth and spontaneous metastasis, we examined growth and metastasis of both estrogen receptor positive (T47D) and ...
Madhavi Puchalapalli   +9 more
doaj   +1 more source

Visualizing the prostate gland by MR imaging in young and old mice. [PDF]

open access: yesPLoS ONE, 2013
Prostate imaging requires optimization in young and old mouse models. We tested which MR sequences and field strengths best depict the prostate gland in young and old mice; and, whether prostate MR signal, size, and architecture change with age.Magnetic ...
Murali Ravoori   +10 more
doaj   +1 more source

Protection of athymic (Nu/Nu) BALB/c mice against Plasmodium berghei by splenocytes from normal (Nu/ +) BALB/c mice

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1985
Athymic BALB/c (Nu/Nu) mice died at 7-13 days after inoculation (DAI) of Plasmodium berghei NK65, whereas their heterozygous (Nu/+) littermates died at 7-8 DAI. Nude (Nu/Nu) mice, reconstituted with 2 x 10(7) splenocytes from uninfected heterozygous (Nu/+
José J. Ferraroni   +2 more
doaj   +1 more source

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