Results 171 to 180 of about 1,780,625 (304)

LepR‐Lineage Cells Represent the Main Target of the Nociceptive CGRP Pathway in White Adipose Tissue Browning

Advanced Science, EarlyView.
Regulation of WAT Browning and UCP1 Expression in LepR‐MSCs of Inguinal WAT by Nociceptive CGRP and Sympathetic Nervous System (SNS) Noradrenaline (NE). ABSTRACT Sympathetic innervation regulates white adipose tissue (WAT) browning; however, the roles of nociceptive neurons and their associated target cells remain unknown.
Yu‐Ting Yen, May Chien, Yan‐Tung Kiu, Ru‐Sing Lee, Hui‐Teng Cheng, Shuei‐Liong Lin, Dong‐Chuan Wu, I‐Hsien Teng, Yi‐Wen Lin, Yi‐Hung Chen, Mien‐Chie Hung, Shih‐Chieh Hung   +11 more
wiley   +1 more source

Roles of Interstitial Albumin in the Subcutaneous Delivery of Therapeutic Peptides

Advanced Science, EarlyView.
A biomimetic extracellular matrix hydrogel platform reveals how interstitial albumin regulates peptide pharmacokinetics after subcutaneous administration. Albumin not only binds peptides but also shows a unique affinity for glycosaminoglycans, thereby reshaping peptide distribution and diffusion.
David Juriga, Anton Norberg, Esther Olaniran Håkansson, Jeroen W. van den Heuvel, Johan Gråsjö, Luke R. Odell, Anna Orlova, Per Hansson   +7 more
wiley   +1 more source

Obesity and Age Elevate Tissue-Resident Microbiota Akkermansia muciniphila to Induce Oxidative Stress and Promote Breast Cancer Risk. [PDF]

Cancer Res
Clear KYJ, Arnone AA, Tsai YT, Wilson AS, Carneiro Buchele ML, Furdui CM, Howard-McNatt M, Chiba A, Soto-Pantoja DR, Tooze JA, Peoples A, Duet ML, Katz AJ, Giri DD, Iyengar NM, Cook KL.   +15 more
europepmc   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source

Effects of Short-Term Energy Limitation at Different Levels With Normal Protein Intake on Hepatic Lipid Metabolism and the Gut Microbiota in Overweight/Obese Mice. [PDF]

Food Sci Nutr
Tian Y, Tang Y, Gu M, Gong J, Zhou Y, He Y, Huang K.   +6 more
europepmc   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Adipose Dysfunction Caused by Obesity and Radiation Therapy Rewires the Prostate Stroma Toward Tumor Progression. [PDF]

Cells
Takkar S, Monga-Wells L, Chatterjee A, Lele SM, Oberley-Deegan RE.   +4 more
europepmc   +1 more source

Fecal Virome Transplantation in Human Disease and Livestock Production: Evidence, Mechanisms, and Translational Challenges

Animal Research and One Health, EarlyView.
Fecal virome transplantation may reshape bacterial communities and host responses while reducing viable bacterial transfer. Preclinical evidence suggests biological activity, but human efficacy remains uncertain, and translation requires product standardization, causal validation, donor–recipient matching, and rigorous biosafety assessment.
Luanyang Shi, Yongjuan Guan, Guanxiang Liang   +2 more
wiley   +1 more source

Gut <i>Enterococcus faecium</i> derived leucic acid mediates the antiobesity effect of dietary fiber. [PDF]

Imeta
Hu B, Gao Q, Hui J, Wang M, Gao H, Li K, Zheng J, Dai Z, Liu S, Liu H.   +9 more
europepmc   +1 more source

Studies on Experimental Obese Mice Part II Pathophysiology of Goldthioglucose Induced and Spontaneously Obese Mice

Folia Endocrinologica Japonica, 1965
openaire   +3 more sources